Oxidative activation of the propolis hapten isoprenyl caffeate.
DOI:
https://doi.org/10.2340/00015555753436Abstract
The reactions of isoprenyl caffeate, the strongest allergen known to be present in propolis, with plausible functional groups of proteins were studied. The thiols glutathione and cysteine, which add to isoprenyl caffeate after having been oxidised to the corresponding quinone, served as model substances. The structure of the thiol adducts was determined by spectroscopic methods, addition being found to occur at C-2. The results support the hypothesis that the catecholic propolis hapten is a pro-hapten that forms a complete antigen after oxidation to caffeate quinone and addition to nucleophilic groups of proteins.Downloads
Download data is not yet available.
Downloads
Published
1995-01-01
How to Cite
Hansson, C., Ezzelarab, M., & Sterner, O. (1995). Oxidative activation of the propolis hapten isoprenyl caffeate. Acta Dermato-Venereologica, 75(1), 34–36. https://doi.org/10.2340/00015555753436
Issue
Section
Articles
License
All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.
Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.
