The polymerase chain reaction and dermatology. A new technique with important implications for the study of skin inflammation and for diagnostic tests of dermatological disorders.

Authors

  • K Paludan
  • K Thestrup-Pedersen

DOI:

https://doi.org/10.2340/000155557316

Abstract

The polymerase chain reaction is a powerful and versatile tool for the analysis of nucleic acids. Through a reaction imitating in vivo DNA replication, a defined fragment of DNA is repeatedly replicated by a DNA polymerase in an exponential manner. Such selective amplification of a sequence of interest has created new possibilities in molecular biology and related sciences. The basic principle and some of its variations and applications for both qualitative and quantitative analyses of potential interest to dermatologists are described.

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Published

1993-02-01

How to Cite

Paludan, K., & Thestrup-Pedersen, K. (1993). The polymerase chain reaction and dermatology. A new technique with important implications for the study of skin inflammation and for diagnostic tests of dermatological disorders. Acta Dermato-Venereologica, 73(1), 1–6. https://doi.org/10.2340/000155557316

Issue

Section

Articles