Epidermodysplasia verruciformis accompanied by familial large granular lymphocytosis and a decrease in T lymphocytes.
DOI:
https://doi.org/10.2340/00015555735254Abstract
A 40/year/old man with epidermodysplasia verruciformis showed a decrease in peripheral blood T cells and abnormal expansion of large granular lymphocytes, accompanied by increased natural killer cell activity. Surface marker analysis of his large granular lymphocytes demonstrated that the subset, CD 57+ and CD 16+, had increased. His father, who had no skin lesions of epidermodysplasia verruciformis, displayed similar blood changes and his brother showed a decrease in T cells and a slight increase in CD 16+ natural killer cells, whereas his mother revealed only a slight decrease in T cells. Our present study indicates that epidermodysplasia verruciformis might be associated with hereditary abnormal expansion of large granular lymphocytes and a decrease in T cells.Downloads
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Published
1993-02-01
How to Cite
Aoyama, H., Seki, S., Abo, T., Usuba, Y., Tomita, Y., & Tagami, H. (1993). Epidermodysplasia verruciformis accompanied by familial large granular lymphocytosis and a decrease in T lymphocytes. Acta Dermato-Venereologica, 73(1), 52–54. https://doi.org/10.2340/00015555735254
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