Abnormalities of lymphocyte function and phenotypic pattern in a case of toxic epidermal necrolysis.
DOI:
https://doi.org/10.2340/0001555572268270Abstract
We examined the blood lymphocyte function and phenotypic pattern in a patient with toxic epidermal necrolysis after taking salazopyrin. We studied cell surface markers, natural killer cell activity and mitogen-induced lymphocyte transformation. Our results point to temporary immunosuppression as evidenced by lymphopenia with a large "null cell" population, reduced natural killer cell activity, and impaired lymphocyte response to mitogens.Downloads
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