Ulstrastructural study of leukodermic skin in Waardenburg-Klein syndrome

Authors

  • H Perrot
  • JP Ortonne
  • J. Thivolet

DOI:

https://doi.org/10.2340/0001555557195200

Abstract

The skin of a patient with Waardenburg syndrome has been studied by electron microscope. In leukodermic skin, there were neither melanocytes nor indeterminate cells; Langerhans cells were normal in number and distribution. On the edge of the lesion, melanocytes were few and appeared degenerated, with abnormal melanosomes; indeterminate cells were observed in suprabasal areas. Healthy skin also showed melanosome abnormalities. These findings are discussed and compared with the characteristics of piebaldism.

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Published

1977-05-01

How to Cite

Perrot, H., Ortonne, J., & Thivolet, J. (1977). Ulstrastructural study of leukodermic skin in Waardenburg-Klein syndrome. Acta Dermato-Venereologica, 57(3), 195–200. https://doi.org/10.2340/0001555557195200

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Section

Articles