Ulstrastructural study of leukodermic skin in Waardenburg-Klein syndrome
DOI:
https://doi.org/10.2340/0001555557195200Abstract
The skin of a patient with Waardenburg syndrome has been studied by electron microscope. In leukodermic skin, there were neither melanocytes nor indeterminate cells; Langerhans cells were normal in number and distribution. On the edge of the lesion, melanocytes were few and appeared degenerated, with abnormal melanosomes; indeterminate cells were observed in suprabasal areas. Healthy skin also showed melanosome abnormalities. These findings are discussed and compared with the characteristics of piebaldism.Downloads
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