Glutathionedopa in malignant melanoma

Authors

  • G Agrup
  • B Falck
  • H Rorsman
  • AM Rosengren
  • E. Rosengren

DOI:

https://doi.org/10.2340/0001555557221222

Abstract

A human melanoma metastasis was found to contain a substance identical with synthetic glutathionedopa when examined by means of an automatic amino acid analyser, chromatography on a Dowex-50 column, thin-layer electrophoresis, and by fluorimetry. The presence of glutathionedopa in melanoma tissue and of enzymes capable of hydrolysing the glutathione moiety of the molecule, together with the absence of glutathionedopa in the urine, suggest that glutathionedopa is an intermediate substance in the formation of 5-S-cysteinyldopa.

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Published

1977-05-01

How to Cite

Agrup, G., Falck, B., Rorsman, H., Rosengren, A., & Rosengren, E. (1977). Glutathionedopa in malignant melanoma. Acta Dermato-Venereologica, 57(3), 221–222. https://doi.org/10.2340/0001555557221222

Issue

Vol. 57 No. 3 (1977)

Section

Articles

License

All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.

Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.

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