Epidermal surface saccharides reactive with phytohemagglutinins and pemphigus antigen
DOI:
https://doi.org/10.2340/0001555552124Abstract
Inorder to study the relationship between epidermal surface saccharides and pemphigus antigen(s), fluorescein-labelled Concanavalin A (Con A) and Phytohemagglutinin-P (PHA-P) were used. These phytohemagglutinins were found to bind with the intercellular areas of human epidermis. Alpha-methyl-D-mannoside and alpha-methyl-D-glucoside inhibited the epidermal intercellular staining pattern produced by ConA-FITC, while N-acetyl-D-galactosamine blocked the same staining pattern produced by PHA-P-FITC. Normal human skin reacted with pemphigus antibody and pemphigus skin with the deposition of IgG both gave a positive intercellular staining pattern with fluorescein labelled phytohemagglutinins. Our data indicated the non-identity of the binding of Con A and PHA-P, and pemphigus antigen(s).Downloads
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Published
1975-01-01
How to Cite
Nishikawa, T., Harada, T., Hatano, H., Ogawa, H., & Miyazaki, H. (1975). Epidermal surface saccharides reactive with phytohemagglutinins and pemphigus antigen. Acta Dermato-Venereologica, 55(1), 21–24. https://doi.org/10.2340/0001555552124
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