Updated Role of High-frequency Ultrasound in Assessing Dermatological Manifestations in Autoimmune Skin Diseases


  • Ke Chai
  • Ruixuan Zhu
  • Fujian Luo
  • Yaqian Shi
  • Minghui Liu
  • Yangfan Xiao Department of Anesthesiology, The Second Xiangya Hospital of Central South University, Changsha, China
  • Rong Xiao Department of Dermatology, The Second Xiangya Hospital of Central South University, Changsha, China




High-frequency ultrasound, Autoimmune skin diseases, Ultrasonic imaging mechanism, Skin pathology


Autoimmune skin diseases are a group of disorders that arise due to the dysregulated immune system attacking self-antigens, causing multiple tissue and organ lesions. With disease progression, the physical and psychological health of patients may be seriously damaged. High-frequency ultrasound is non-invasive, reproducible, and suitable for visualizing the fine structure of external organs. The usage of high-frequency ultrasound has increased in recent years in the auxiliary diagnosis and monitoring of various skin diseases; it serves as a promising tool for dermatological disease assessment. This review summarizes the characteristics of high-frequency ultrasound imaging in common autoimmune skin diseases, including systemic lupus erythematosus, scleroderma, psoriasis, dermatomyositis, and pemphigus/pemphigoid. The objective of this review is to provide new ideas and strategies for dermatologists to diagnose and track the prognosis of autoimmune skin diseases.


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How to Cite

Chai, K., Zhu, R., Luo, F., Shi, Y., Liu, M., Xiao, Y. ., & Xiao, R. (2022). Updated Role of High-frequency Ultrasound in Assessing Dermatological Manifestations in Autoimmune Skin Diseases. Acta Dermato-Venereologica, 102, adv00765. https://doi.org/10.2340/actadv.v102.1969

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