Impact of Childhood Onset Psoriasis on Addictive Behaviours, Socioeconomic and Educational Data in Adulthood
Keywords:psoriasis, children, adolescent, socioeconomic data, educational level, alcohol, tobacco
Paediatric psoriasis has been associated with school absenteeism, limitation of physical activities, psychiatric disorders and, in the longer term, with sexual dysfunction and addictions. This raises the hypothesis that childhood onset psoriasis may affect patients’ educational development, and further social and professional outcomes. This study evaluated the relationship between childhood onset psoriasis and patients’ educational and socioeconomic characteristics, and the development of addictions in adulthood. This cross-sectional ancillary study captured patients’ characteristics at baseline in the French PSOBIOTEQ registry. Data in adulthood included: educational (baccalaureate) and socioeconomic (working activity) groups, smoking status (self-reporting of being a current smoker vs past smoker or non-smoker), alcohol consumption (defined as at least 1 glass of alcoholic beverage per day), and living conditions (alone/family/social institutions; child at home). A total of 1,960 patients were included, of whom 26.2% had childhood onset psoriasis. In multivariate analyses, childhood onset psoriasis was associated with smoker status (p = 0.02). No association was observed with educational level, working activity, living conditions, or alcohol consumption. This study provides reassuring data overall with regard to the impact of childhood onset psoriasis on major social outcomes. Evidence for some association with addictive behaviours paves the way for larger prospective studies assessing in depth the social and educational impact of this disease.
Gelfand JM, Weinstein R, Porter SB, Neimann AL, Berlin JA, Margolis DJ. Prevalence and treatment of psoriasis in the United Kingdom: a population-based study. Arch Dermatol 2005; 141: 1537-1541.
https://doi.org/10.1001/archderm.141.12.1537 DOI: https://doi.org/10.1001/archderm.141.12.1537
Augustin M, Glaeske G, Radtke MA, Christophers E, Reich K, Schäfer I. Epidemiology and comorbidity of psoriasis in children. Br J Dermatol 2010; 162: 633-636.
https://doi.org/10.1111/j.1365-2133.2009.09593.x DOI: https://doi.org/10.1111/j.1365-2133.2009.09593.x
Mahé E. Childhood psoriasis. Eur J Dermatol 2016; 26: 537-548.
https://doi.org/10.1684/ejd.2016.2932 DOI: https://doi.org/10.1684/ejd.2016.2932
Ferrándiz C, Pujol RM, García-Patos V, Bordas X, Smandía JA. Psoriasis of early and late onset: a clinical and epidemiologic study from Spain. J Am Acad Dermatol 2002; 46: 867-873.
https://doi.org/10.1067/mjd.2002.120470 DOI: https://doi.org/10.1067/mjd.2002.120470
De Jager ME, de Jong EM, Meeuwis KA, van de Kerkhof PC, Seyger MM. No evidence found that childhood onset of psoriasis influences disease severity, future body mass index or type of treatments used. J Eur Acad Dermatol Venereol 2010; 24: 1333-1339.
https://doi.org/10.1111/j.1468-3083.2010.03645.x DOI: https://doi.org/10.1111/j.1468-3083.2010.03645.x
Mahé E, Maccari F, Beauchet A, Lahfa M, Barthelemy H, Reguiaï Z, et al. Childhood-onset psoriasis: association with future cardiovascular and metabolic comorbidities. Br J Dermatol 2013; 169: 889-895.
https://doi.org/10.1111/bjd.12441 DOI: https://doi.org/10.1111/bjd.12441
Bronckers IMGJ, Bruins FM, van Geel MJ, Groenewoud HMM, Kievit W, van de Kerkhof PCM, et al. Nail involvement as a predictor of disease severity in paediatric psoriasis: follow-up data from the Dutch ChildCAPTURE registry. Acta Derm Venereol 2019; 99: 152-157.
https://doi.org/10.2340/00015555-3036 DOI: https://doi.org/10.2340/00015555-3036
Pourchot D, Bodemer C, Phan A, Bursztejn AC, Hadj-Rabia S, Boralevi F, et al. Nail psoriasis: a systematic evaluation in 313 children with psoriasis. Pediatr Dermatol 2017; 34: 58-63.
https://doi.org/10.1111/pde.13028 DOI: https://doi.org/10.1111/pde.13028
Randa H, Todberg T, Skov L, Larsen LS, Zachariae R. Health-related quality of life in children and adolescents with psoriasis: a systematic review and meta-analysis. Acta Derm Venereol 2017; 97: 555-563.
https://doi.org/10.2340/00015555-2600 DOI: https://doi.org/10.2340/00015555-2600
Ramsay B, O'Reagan M. A survey of the social and psychological effects of psoriasis. Br J Dermatol 1988; 118: 195-201.
https://doi.org/10.1111/j.1365-2133.1988.tb01774.x DOI: https://doi.org/10.1111/j.1365-2133.1988.tb01774.x
Bilgic A, Bilgic Ö, Akış HK, Eskioğlu F, Kılıç EZ. Psychiatric symptoms and health-related quality of life in children and adolescents with psoriasis. Pediatr Dermatol 2010; 27: 614-617.
https://doi.org/10.1111/j.1525-1470.2010.01195.x DOI: https://doi.org/10.1111/j.1525-1470.2010.01195.x
Carter-Pokras OD, Bugbee BA, Lauver PE, Aiken R, Arria AM. Utilizing student health and academic data: a county-level demonstration project. Health Promot Pract 2021; 22: 193-203.
https://doi.org/10.1177/1524839919862796 DOI: https://doi.org/10.1177/1524839919862796
Zink A, Herrmann M, Fischer T, Lauffer F, Garzorz-Stark N, Böhner A, et al. Addiction: an underestimated problem in psoriasis health care. J Eur Acad Dermatol Venereol 2017; 31: 1308-1315.
https://doi.org/10.1111/jdv.14204 DOI: https://doi.org/10.1111/jdv.14204
Caroppo F, Zacchino M, Milazzo E, Fontana E, Nobile F, Marogna C, et al. Quality of life in children with psoriasis: results from a monocentric study. Ital J Dermatol Venerol 2021; 156: 374-377.
https://doi.org/10.23736/S2784-8671.19.06368-5 DOI: https://doi.org/10.23736/S2784-8671.19.06368-5
Sbidian E, Giboin C, Bachelez H, Paul C, Beylot-Barry M, Dupuy A, et al. Factors associated with the choice of the first biologic in a psoriasis: real life analysis from the Psobioteq cohort. J Eur Acad Dermatol Venereol 2017; 31: 2046-2054.
https://doi.org/10.1111/jdv.14406 DOI: https://doi.org/10.1111/jdv.14406
Masson Regnault M, Castañeda-Sanabria J, Diep Tran MHT, Beylot-Barry M, Bachelez H, Beneton N, et al. Users of biologics in clinical practice: would they be eligible for phase III clinical studies? Cohort Study in the French Psoriasis Registry PSOBIOTEQ. J Eur Acad Dermatol Venereol 2020; 34: 293-300.
https://doi.org/10.1111/jdv.15878 DOI: https://doi.org/10.1111/jdv.15878
Beck F, Guilbert P, Gautier A, editors. Baromètre Santé 2005. Edition INPES, Saint-Denis, France; 2007.
Ewald DR, Strack RW, Orsini MM. Rethinking addiction. Glob Pediatr Health 2019 23; 6: 2333794X18821943.
https://doi.org/10.1177/2333794X18821943 DOI: https://doi.org/10.1177/2333794X18821943
Mahé E, Bursztejn AC, Phan A, Corgibet F, Beauchet A. Management of childhood psoriasis in France. A national survey among general practitioners, pediatricians, and dermatologists. Dermatol Ther 2018; 31: e12567.
https://doi.org/10.1111/dth.12567 DOI: https://doi.org/10.1111/dth.12567
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Copyright (c) 2022 Emmanuel Mahé, Florence Tubach, Denis Jullien, Diep Tran, Carle Paul, Marie Beylot-Barry, Alain Dupuy, Manuelle Viguier, Marie-Aleth Richard, Emilie Sbidian, Nathalie Beneton, Pascal Joly, Olivier Chosidow, Hervé Bachelez
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