Characterizing Patients and Treatment Patterns in Moderate-to-severe Atopic Dermatitis in Finland: A Population-based Study Using National Health Data

Authors

  • Anita Remitz Department of Dermatology and Allergology at University of Helsinki, Helsinki, Finland
  • Essi J. Peltonen Oriola, Espoo, Finland
  • Laura Korhonen Allergy Centre, Tampere University Hospital, Tampere, Finland
  • Pekka Nortamo Oy Eli Lilly Finland Ab, Helsinki, Finland
  • Ilona Iso-Mustajärvi Oriola, Espoo, Finland
  • Tuire Prami Oriola, Espoo, Finland
  • Lasse Oinonen Oy Eli Lilly Finland Ab, Helsinki, Finland
  • Beatrice Gittens Eli Lilly and Company Ltd, Basingstoke, UK
  • Lill-Brith Von Arx Eli Lilly Danmark A/S, Herlev, Denmark
  • Vibeke Porsdal Eli Lilly Danmark A/S, Herlev, Denmark

DOI:

https://doi.org/10.2340/actadv.v105.41244

Keywords:

Atopic dermatitis, observational study, patient characteristics, clinical practice patterns

Abstract

This observational study evaluated demographics, disease characteristics, and treatment patterns in children, adolescents, and adults with moderate-to-severe atopic dermatitis (AD) and compared comorbidities (adults only) and healthcare resource use with those of matched reference subjects without moderate-to-severe AD in Finland between 2016 and 2020. A total of 68,216 patients with moderate-to-severe AD and a reference population of 338,325 people without moderate-to-severe AD were identified and included in the study. Among children aged 0–11 years in the moderate-to-severe AD cohort, most were diagnosed with AD and were identified to have moderate-to-severe AD before they reached 4 years of age (92.4% and 79.3%, respectively). Atopic disorders and psychiatric, gastrointestinal, and other diseases were more common in adults with moderate-to-severe AD than in the reference population. Regardless of age, patients with moderate-to-severe AD had a higher number of primary and secondary healthcare visits annually compared with the reference population. Across all 3 age groups, topical corticosteroids and emollients were the 2 categories of AD medications most frequently used throughout the study period. In adults, the use of methotrexate and dupilumab increased over the course of the study. Moderate-to-severe AD affects people of all ages in Finland.

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Additional Files

Published

2025-04-24

How to Cite

Remitz, A., Peltonen, E. J., Korhonen, L., Nortamo, P., Iso-Mustajärvi, I., Prami, T., … Porsdal, V. (2025). Characterizing Patients and Treatment Patterns in Moderate-to-severe Atopic Dermatitis in Finland: A Population-based Study Using National Health Data. Acta Dermato-Venereologica, 105, adv41244. https://doi.org/10.2340/actadv.v105.41244

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