Is the Increase in Tumour Markers and Hashimoto’s Thyroiditis an Incidental Event During Dupilumab Treatment? A Case Report

Authors

  • Kesheng Lin Department of Dermatology, Zhejiang Chinese Medical University, Hangzhou, China
  • Weijie Shen Department of Dermatology, Zhejiang Chinese Medical University, Hangzhou, China
  • Nailiang Lin Department of Pharmacy, Pingyang Traditional Chinese Medicine Hospital of Zhejiang University of Traditional Chinese Medicine, Wenzhou, China
  • Sijia Li Department of Dermatology, Zhejiang Chinese Medical University, Hangzhou, China
  • Liming Wu Department of Dermatology, Affiliated Hangzhou First People’s Hospital, West Lake University School of Medicine , Hangzhou, P. R. China

DOI:

https://doi.org/10.2340/actadv.v105.41250

Keywords:

atopic dermatitis, autoimmune disease, biological therapy, neoplasms

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References

Owji S, Ungar B, Dubin DP, Poplausky D, Young JN, Ghalili S, et al. No association between dupilumab use and short-term cancer development in atopic dermatitis patients. J Allergy Clin Immunol Pract 2023; 11: 1548-1551.

https://doi.org/10.1016/j.jaip.2022.12.018 DOI: https://doi.org/10.1016/j.jaip.2022.12.018

Siliquini N, Viola R, Giura MT, Fierro MT, Ribero S, Ortoncelli M. Case of bladder cancer during Dupilumab therapy: Just an incidental event? Dermatol Ther 2020; 33: e13854.

https://doi.org/10.1111/dth.13854 DOI: https://doi.org/10.1111/dth.13854

Harb H, Chatila TA. Mechanisms of Dupilumab. Clin Exp Allergy 2020; 50: 5-14.

https://doi.org/10.1111/cea.13491 DOI: https://doi.org/10.1111/cea.13491

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Moriyama M, Nakamura S. Th1/Th2 immune balance and other T helper subsets in IgG4-related disease. Curr Top Microbiol Immunol 2017; 401: 75-83.

https://doi.org/10.1007/82_2016_40 DOI: https://doi.org/10.1007/82_2016_40

Mazziotti G, Sorvillo F, Naclerio C, Farzati A, Cioffi M, Perna R, et al. Type-1 response in peripheral CD4+ and CD8+ T cells from patients with Hashimoto's thyroiditis. Eur J Endocrinol 2003; 148: 383-388.

https://doi.org/10.1530/eje.0.1480383 DOI: https://doi.org/10.1530/eje.0.1480383

Matsuda T, Yamada H, Hida N, NakaizumiT, Yamada E, Satoh H, et al. An asthmatic case of psoriasiform eruption caused by administration of dupilumab. Allergol Int 2020; 69: 478-479.

https://doi.org/10.1016/j.alit.2020.02.004 DOI: https://doi.org/10.1016/j.alit.2020.02.004

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Published

2025-02-05

How to Cite

Lin, K., Shen, W., Lin, N., Li, S., & Wu, L. (2025). Is the Increase in Tumour Markers and Hashimoto’s Thyroiditis an Incidental Event During Dupilumab Treatment? A Case Report. Acta Dermato-Venereologica, 105, adv41250. https://doi.org/10.2340/actadv.v105.41250

Issue

Vol. 105 (2025)

Section

Short Communication

Categories

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Copyright (c) 2025 Kesheng Lin, Weijie Shen, Nailiang Lin, Sijia Li, Liming Wu

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.

Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.

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