A Case of Tertiary Syphilis with Unilateral Pupillary Abnormality

Authors

  • Laura Glismann Department of Dermato-Venereology, Bispebjerg University Hospital, Copenhagen, Denmark; Department of Bacteria, Parasites & Fungi, Statens Serum Institut, Copenhagen, Denmark
  • Simone Høstgaard Department of Dermato-Venereology, Bispebjerg University Hospital, Copenhagen, Denmark; Department of Bacteria, Parasites & Fungi, Statens Serum Institut, Copenhagen, Denmark
  • Christos Christakopoulos Department of Ophthalmology, Næstved Hospital, Region Zealand, Denmark
  • Jørgen Skov Jensen Department of Bacteria, Parasites & Fungi, Statens Serum Institut, Copenhagen, Denmark
  • Kirsten Salado-Rasmussen Department of Dermato-Venereology, Bispebjerg University Hospital, Copenhagen, Denmark; Department of Bacteria, Parasites & Fungi, Statens Serum Institut, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

DOI:

https://doi.org/10.2340/actadv.v105.43120

Keywords:

Syphilis, Neurosyphilis, tertiary syphilis

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References

Clark EG, Danbolt N. The Oslo study of the natural history of untreated syphilis; an epidemiologic investigation based on a restudy of the Boeck–Bruusgaard material; a review and appraisal. J Chronic Dis 1955; 2: 311–344.

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Ekselius L, Gerdin B, Vahlquist A. The syphilis pandemic prior to penicillin: origin, health issues, cultural representation and ethical challenges. Acta Derm Venereol 2024; 104: adv34879.

https://doi.org/10.2340/actadv.v104.34879 DOI: https://doi.org/10.2340/actadv.v104.34879

Adie WJ. Pseudo-Argyll Robertson pupils with absent tendon reflexes: a benign disorder simulating tabes dorsalis. Br Med J 1931; 1: 928–930.

https://doi.org/10.1136/bmj.1.3673.928 DOI: https://doi.org/10.1136/bmj.1.3673.928

Lukehart SA. Syndromes of tertiary syphilis. In: Holmes KK, Sparling PF, Stamm WE, Piot P, Wasserheit JN, Corey L, et al., editors. Sexually transmitted diseases. New York: McGraw Hill; 2008. p. 669.

Dutta Majumder P, Chen EJ, Shah J, Ching Wen Ho D, Biswas J, See Yin L, et al. Ocular syphilis: an update. Ocul Immunol Inflamm 2019; 27: 117–125.

https://doi.org/10.1080/09273948.2017.1371765 DOI: https://doi.org/10.1080/09273948.2017.1371765

Thompson HS, Kardon RH. The Argyll Robertson pupil. J Neuroophthalmol 2006; 26: 134–138.

https://doi.org/10.1097/01.wno.0000222971.09745.91 DOI: https://doi.org/10.1097/01.wno.0000222971.09745.91

Tatu L, Bogousslavsky J. Tabes dorsalis in the 19(th) century: the golden age of progressive locomotor ataxia. Rev Neurol 2021; 177: 376–384.

https://doi.org/10.1016/j.neurol.2020.10.006 DOI: https://doi.org/10.1016/j.neurol.2020.10.006

Bhandari J, Thada PK, Leslie SW, Ratzan RM. Tabes dorsalis. StatPearls. Treasure Island, FL: StatPearls Publishing; 2024.

Published

2025-03-20

How to Cite

Glismann, L., Høstgaard, S., Christakopoulos, C., Jensen, J. S., & Salado-Rasmussen, K. (2025). A Case of Tertiary Syphilis with Unilateral Pupillary Abnormality. Acta Dermato-Venereologica, 105, adv43120. https://doi.org/10.2340/actadv.v105.43120

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Research letter

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