Cutaneous Squamous Cell Carcinoma in the Post-COVID-19 Era: Dramatic Increase of New Cases in 2023 in Two German Skin Tumour Centers
DOI:
https://doi.org/10.2340/actadv.v105.43609Keywords:
cutaneous squamous cell carcinoma, incidence, COVID-19 pandemic, SARS-CoV-2 pandemic, post-COVID-19 eraDownloads
References
Hu W, Fang L, Ni R, Zhang H, Pan G. Changing trends in the disease burden of non-melanoma skin cancer globally from 1990 to 2019 and its predicted level in 25 years. BMC Cancer 2022; 22: 836.
https://doi.org/10.1186/s12885-022-09940-3 DOI: https://doi.org/10.1186/s12885-022-09940-3
Zhou L, Zhong Y, Han L, Xie Y, Wan M. Global, regional, and national trends in the burden of melanoma and non-melanoma skin cancer: insights from the global burden of disease study 1990–2021. Sci Rep 2025; 15: 5996.
https://doi.org/10.1038/s41598-025-90485-3 DOI: https://doi.org/10.1038/s41598-025-90485-3
Decker KM, Feely A, Bucher O, Czaykowski P, Hebbard P, Kim JO, et al. New cancer diagnoses before and during the COVID-19 pandemic. JAMA Netw Open 2023; 6: e2332363.
https://doi.org/10.1001/jamanetworkopen.2023.32363 DOI: https://doi.org/10.1001/jamanetworkopen.2023.32363
Wall J, Gadsby-Davis K, Mistry K, Levell NJ, Venables ZC. Impact of the COVID-19 pandemic on international cutaneous squamous cell carcinoma incidence: a systematic review and meta-analysis. Skin Health Dis 2024; 4: e405.
https://doi.org/10.1002/ski2.405 DOI: https://doi.org/10.1002/ski2.405
Kleemann J, Meissner M, Özistanbullu D, Balaban Ü, Old O, Kippenberger S, et al. Impact of the Covid-19 pandemic on melanoma and non-melanoma skin cancer inpatient treatment in Germany: a nationwide analysis. J Eur Acad Dermatol Venereol 2022; 36: 1766–1773.
https://doi.org/10.1111/jdv.18217 DOI: https://doi.org/10.1111/jdv.18217
Balakirski G, Assaf C, Dippel E, Fröhlich A, Kofler L, Kreuter A, et al. Auswirkungen der COVID-19-Pandemie auf die stationäre Dermatochirurgie in Deutschland. Retrospektive Auswertung der operativen Fälle aus neun Hautkliniken. Dermatologie (Heidelb) 2024; 75: 864–877.
https://doi.org/10.1007/s00105-024-05417-5 DOI: https://doi.org/10.1007/s00105-024-05417-5
Balakirski G, Sabulyte S, Wesselmann U, Michalowitz AL, Kreuter A, Hofmann SC. Long-term effects of the COVID-19 pandemic on cutaneous squamous cell carcinoma: increase of thick tumors in two German dermatology clinics. J Dtsch Dermatol Ges 2023; 21: 910–913.
https://doi.org/10.1111/ddg.15087 DOI: https://doi.org/10.1111/ddg.15087
Shahid S, Gao J, Corriero AC, Roszpopa J, Miranda BH. A study of the effects of delayed patient presentation on cutaneous SCC progression. J Plast Reconstr Aesthet Surg 2022; 75: 722–729.
https://doi.org/10.1016/j.bjps.2021.09.015 DOI: https://doi.org/10.1016/j.bjps.2021.09.015
Taccioli F, Blessent CGF, Paganelli A, Fagioli F, Chester JM, Kaleci S, et al. Delay in cutaneous squamous cell carcinoma diagnosis due to interrupted services is associated with worse prognoses and modified surgical approaches. Cancers (Basel) 2024; 16: 1469.
https://doi.org/10.3390/cancers16081469 DOI: https://doi.org/10.3390/cancers16081469
Díaz-Calvillo P, Sánchez-Díaz M, Rodríguez-Pozo JÁ, Martínez-Ruiz V, Martínez-López A, Arias-Santiago S. Impact of COVID-19 pandemic on cutaneous squamous cell carcinoma: a single-centre study of epidemiologic, clinic and histopathological factors. Actas Dermosifiliogr 2024; 115: 224–230.
https://doi.org/10.1016/j.ad.2023.10.003 DOI: https://doi.org/10.1016/j.ad.2023.10.003
Sangers TE, Wakkee M, Kramer-Noels EC, Nijsten T, Louwman MWJ, Jaspars EH, et al. Limited impact of COVID-19-related diagnostic delay on cutaneous melanoma and squamous cell carcinoma tumour characteristics: a nationwide pathology registry analysis. Br J Dermatol 2022; 187: 196–202.
https://doi.org/10.1111/bjd.21050 DOI: https://doi.org/10.1111/bjd.21050
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Copyright (c) 2025 Peter Mrotzek, Silke C. Hofmann, Alexander Kreuter, Sebastian Appelbaum, Ulrich Wesselmann, Ulrich Peter Wehry, Galina Balakirski

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