Topical Metronidazole Versus Ivermectin for Low-density Demodex Rosacea: A Rater-blinded, Randomized, Split-face Trial

Authors

  • Marvin Chia-Han Yeh Department of Dermatology, Wan Fang Hospital, Taipei Medical University, 111, Hsing-Long Road Sec 3, Wenshan District, Taipei City 116, Taiwan
  • Jerry Tsai Johns Hopkins University School of Medicine, Baltimore, MD, USA
  • Yu Chen Huang Department of Dermatology, Wan Fang Hospital, Taipei Medical University, 111, Hsing-Long Road Sec 3, Wenshan District, Taipei City 116, Taiwan; 3Department of Dermatology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan;  4Research Center of Big Data and Meta-analysis, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan
  • Hsiao-Han Wang Department of Dermatology, Wan Fang Hospital, Taipei Medical University, 111, Hsing-Long Road Sec 3, Wenshan District, Taipei City 116, Taiwan;  4Research Center of Big Data and Meta-analysis, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan

DOI:

https://doi.org/10.2340/actadv.v102.4391

Keywords:

demodex, ivermectin, metronidazole, rosacea

Abstract

Abstract is missing (Short communication)

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References

Huang HP, Hsu CK, Lee JY. Rosacea with persistent facial erythema and high Demodex density effectively treated with topical ivermectin alone or combined with oral carvedilol. Dermatol Ther 2021; 34: e14899.

https://doi.org/10.1111/dth.14899 DOI: https://doi.org/10.1111/dth.14899

Huang HP, Hsu CK, Lee JY. Thumbnail-squeezing method: an effective method for assessing Demodex density in rosacea. J Eur Acad Dermatol Venereol. 2020; 34: e343-e345.

https://doi.org/10.1111/jdv.16321 DOI: https://doi.org/10.1111/jdv.16321

Aşkin U, Seçkin D. Comparison of the two techniques for measurement of the density of Demodex folliculorum: standardized skin surface biopsy and direct microscopic examination. Br J Dermatol 2010; 162: 1124-1126.

https://doi.org/10.1111/j.1365-2133.2010.09645.x DOI: https://doi.org/10.1111/j.1365-2133.2010.09645.x

Kawata AK, Revicki DA, Thakkar R, Jiang P, Krause S, Davidson MH, et al. Flushing ASsessment Tool (FAST): psychometric properties of a new measure assessing flushing symptoms and clinical impact of niacin therapy. Clin Drug Investig 2009; 29: 215-229.

https://doi.org/10.2165/00044011-200929040-00001 DOI: https://doi.org/10.2165/00044011-200929040-00001

Ventre E, Rozières A, Lenief V, Albert F, Rossio P, Laoubi L, et al. Topical ivermectin improves allergic skin inflammation. Allergy 2017; 72: 1212-1221.

https://doi.org/10.1111/all.13118 DOI: https://doi.org/10.1111/all.13118

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Published

2022-11-07

How to Cite

Yeh, M. C.-H., Tsai, J., Huang, Y. C., & Wang, . H.-H. (2022). Topical Metronidazole Versus Ivermectin for Low-density Demodex Rosacea: A Rater-blinded, Randomized, Split-face Trial. Acta Dermato-Venereologica, 102, adv00811. https://doi.org/10.2340/actadv.v102.4391

Issue

Vol. 102 (2022)

Section

Short Communication

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Copyright (c) 2022 Marvin Chia-Han Yeh, Jerry Tsai, Yu Chen Huang, Hsiao-Han Wang

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Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.

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