Rapidly Progressing CD8-negative Hypopigmented Mycosis Fungoides in Adult Caucasian Male with Good Response to Mogamulizumab

Authors

  • Agnieszka Kimak-Pielas Department of Dermatology, Medical University of Lodz, Łódź, Poland; Department of Dermatology and Venereology, Teaching Hospital No 2, Łódź, Poland
  • Taduesz Robak Department of Haematology, Medical University of Łódź, Lodz, Poland; Department of General Haematology, Copernicus Memorial Hospital, Łódź, Poland
  • Marcin Braun Department of Pathology, Medical University of Lodz, Łódź, Poland
  • Agnieszka Żebrowska Department of Dermatology, Medical University of Lodz, Łódź, Poland; Department of Dermatology and Venereology, Teaching Hospital No 2, Łódź, Poland
  • Ewa Robak Department of Dermatology, Medical University of Lodz, Łódź, Poland; Department of Dermatology and Venereology, Teaching Hospital No 2, Łódź, Poland

DOI:

https://doi.org/10.2340/actadv.v105.43932

Keywords:

cucutaneous T-cell lymphoma, mogamulizumab, mycosis fungoides

Abstract

Hypopigmented mycosis fungoides is a rare variant of mycosis fungoides often seen in younger patients and individuals with darker skin tones and is characterized by hypopigmented patches or plaques. The lesions are usually asymptomatic and respond well to topical treat-ment or phototherapy. This article presents a case of an adult Caucasian male with a rare variant of CD8-negativeh hypopigmented mycosis fungoides, with a rapid progression to erythrodermic lesions, failure of standard treatment, and a good response to mogamulizumab.

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References

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Published

2025-12-18

How to Cite

Kimak-Pielas, A., Robak, T., Braun, M., Żebrowska, A., & Robak, E. (2025). Rapidly Progressing CD8-negative Hypopigmented Mycosis Fungoides in Adult Caucasian Male with Good Response to Mogamulizumab. Acta Dermato-Venereologica, 105, adv43932. https://doi.org/10.2340/actadv.v105.43932

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