The Regression Heterogeneity Pattern of Infantile Haemangiomas after Treatment with Propranolol: A Multicentre Retrospective Study

Authors

  • Kaizhi Zhang Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, China
  • Maierhaba Tuersuntuoheti Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, China
  • Wei Shan Department of Pediatric Surgery, Sichuan Women and Children’s Hospital, Chengdu, China
  • Fan Hu Department of Vascular & Interventional Radiology, West China Second University Hospital of Sichuan University, Chengdu, China
  • Yi Ji Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, China https://orcid.org/0000-0002-9289-9660

DOI:

https://doi.org/10.2340/actadv.v105.44079

Keywords:

infantile hemangioma, propranolol, clinical characteristics, heterogeneity

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References

Munden A, Butschek R, Tom WL, Marshall JS, Poeltler DM, Krohne SE, et al. Prospective study of infantile haemangiomas: incidence, clinical characteristics and association with placental anomalies. Br J Dermatol 2014; 170: 907–913. DOI: https://doi.org/10.1111/bjd.12804

Krowchuk DP, Frieden IJ, Mancini AJ, Darrow DH, Blei F, Greene AK, et al. Clinical practice guideline for the management of infantile hemangiomas. Pediatrics 2019; 143: e20183475. DOI: https://doi.org/10.1542/peds.2018-3475

Rodríguez Bandera AI, Sebaratnam DF, Wargon O, Wong LF. Infantile hemangioma. Part 1: Epidemiology, pathogenesis, clinical presentation and assessment. J Am Acad Dermatol 2021; 85: 1379–1392. DOI: https://doi.org/10.1016/j.jaad.2021.08.019

Macca L, Altavilla D, Di Bartolomeo L, Irrera N, Borgia F, Li Pomi F, et al. Update on treatment of infantile hemangiomas: what’s new in the last five years. Front Pharmacol 2022; 13: 879602. DOI: https://doi.org/10.3389/fphar.2022.879602

Zhang K, Xiang S, Zhou J, Qiu T, Lan Y, Ji Y. PHACE syndrome: looking backward and forward. Orphanet J Rare Dis 2025; 20: 345. DOI: https://doi.org/10.1186/s13023-025-03899-7

Metry D, Copp HL, Rialon KL, Iacobas I, Baselga E, Dobyns WB, et al. Delphi consensus on diagnostic criteria for LUMBAR syndrome. J Pediatr 2024; 272: 114101. DOI: https://doi.org/10.1016/j.jpeds.2024.114101

Weitz NA, Bayer ML, Baselga E, Torres M, Siegel D, Drolet BA, et al. The “biker-glove” pattern of segmental infantile hemangiomas on the hands and feet. J Am Acad Dermatol 2014; 71: 542–547. DOI: https://doi.org/10.1016/j.jaad.2014.04.062

Janmohamed SR, de Waard-van der Spek FB, Madern GC, de Laat PC, Hop WC, Oranje AP. Scoring the proliferative activity of haemangioma of infancy: the Haemangioma Activity Score (HAS). Clin Exp Dermatol 2011; 36: 715–723. DOI: https://doi.org/10.1111/j.1365-2230.2011.04080.x

Published

2025-09-23

How to Cite

Zhang, K., Tuersuntuoheti, M., Shan, W., Hu, F., & Ji, Y. (2025). The Regression Heterogeneity Pattern of Infantile Haemangiomas after Treatment with Propranolol: A Multicentre Retrospective Study. Acta Dermato-Venereologica, 105, adv44079. https://doi.org/10.2340/actadv.v105.44079

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