Commentary on: "The Effects of Sun Exposure and Pigmentation Phenotype on Prognosis in Metastatic Melanoma"

Authors

  • Marit B. Veierød Oslo Centre for Biostatistics and Epidemiology, Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway https://orcid.org/0000-0002-2083-2758
  • Morten Valberg Oslo Centre for Biostatistics and Epidemiology, Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway https://orcid.org/0009-0006-7992-5023
  • Adele C. Green Department of Population Health, QIMR Berghofer Medical Research Institute, Brisbane, Australia; Cancer Research UK Manchester Institute, University of Manchester, Manchester, United Kingdom https://orcid.org/0000-0002-2753-4841
  • Flavie Perrier Oslo Centre for Biostatistics and Epidemiology, Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway https://orcid.org/0000-0001-6979-9656

DOI:

https://doi.org/10.2340/actadv.v106.adv-2026-0741

Keywords:

melanoma, sunburn, death, selection bias

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References

Svensson T, Sahlberg S, Carneiro A, Isaksson K, Nielsen K, Ekedahl H. The effects of sun exposure and pigmentation phenotype on prognosis in metastatic melanoma. Acta Derm Venereol 2026; 106: 0388. DOI: https://doi.org/10.2340/actadv.v106.adv-2026-0388

Loo K, Soliman I, Renzetti M, Li T, Wu H, Reddy S, et al. Impact of sun exposure and tanning patterns on next-generation sequencing mutations in melanoma. J Surg Res 2020; 254: 147–153. DOI: https://doi.org/10.1016/j.jss.2020.04.021

Snyder A, Makarov V, Merghoub T, Yuan J, Zaretsky JM, Desrichard A, et al. Genetic basis for clinical response to CTLA-4 blockade in melanoma. N Engl J Med 2014; 371: 2189–2199. DOI: https://doi.org/10.1056/NEJMoa1406498

Fortman D, Karunamurthy A, Hartman D, Wang H, Seigh L, Abukhiran I, et al. Automated quantitative CD8+ tumor-infiltrating lymphocytes and tumor mutation burden as independent biomarkers in melanoma patients receiving front-line anti-PD-1 immunotherapy. Oncologist 2024; 29: 619–628. DOI: https://doi.org/10.1093/oncolo/oyae054

Berwick M, Armstrong BK, Ben-Porat L, Fine J, Kricker A, Eberle C, et al. Sun exposure and mortality from melanoma. J Natl Cancer Inst 2005; 97: 195–199. DOI: https://doi.org/10.1093/jnci/dji019

Berwick M, Reiner AS, Paine S, Armstrong BK, Kricker A, Goumas C, et al. Sun exposure and melanoma survival: a GEM study. Cancer Epidemiol Biomarkers Prev 2014; 23: 2145–2152. DOI: https://doi.org/10.1158/1055-9965.EPI-14-0431

Perrier F, Ahimbisibwe A, Valberg M, Green AC, Ghiasvand R, Rueegg CS, et al. Exploring the paradoxical association of sun exposure and melanoma-specific mortality: The Norwegian Women and Health (NOWAC) Study. Eur J Cancer 2026; 241: 116787. DOI: https://doi.org/10.1016/j.ejca.2026.116787

Published

2026-06-30

How to Cite

Veierød, M. B., Valberg, M., Green, A. C., & Perrier, F. (2026). Commentary on: "The Effects of Sun Exposure and Pigmentation Phenotype on Prognosis in Metastatic Melanoma". Acta Dermato-Venereologica, 106, adv–2026. https://doi.org/10.2340/actadv.v106.adv-2026-0741

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