Body Composition, Cardiometabolic Risk Factors and Comorbidities in Psoriasis and the Effect of HLA-C*06:02 Status: The HUNT Study, Norway

Authors

  • Åshild Øksnevad Solvin K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU - Norwegian University of Science and Technology, Trondheim, Norway
  • Vera V. Bjarkø K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU - Norwegian University of Science and Technology, Trondheim, Norway https://orcid.org/0000-0002-7769-8780
  • Laurent F. Thomas K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU - Norwegian University of Science and Technology, Trondheim, Norway https://orcid.org/0000-0003-0548-2486
  • Patricia Berrospi K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU - Norwegian University of Science and Technology, Trondheim, Norway
  • Kristian Hveem K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU - Norwegian University of Science and Technology, Trondheim, Norway https://orcid.org/0000-0001-8157-9744
  • Marit Saunes Department of Dermatology, Clinic of Orthopedics, Rheumatology and Dermatology, St. Olavs hospital, Trondheim University Hospital, Trondheim, Norway https://orcid.org/0000-0001-5177-9390
  • Bjørn O. Åsvold K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU - Norwegian University of Science and Technology, Trondheim, Norway https://orcid.org/0000-0003-3837-2101
  • Mari Løset K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU - Norwegian University of Science and Technology, Trondheim, Norway https://orcid.org/0000-0003-3736-6551

DOI:

https://doi.org/10.2340/actadv.v103.5209

Keywords:

Comorbidity, Epidemiology, Genetics, Psoriasis

Abstract

Abstract is missing (Short communication)

Downloads

Download data is not yet available.

References

Parisi R, Iskandar IYK, Kontopantelis E, Augustin M, Griffiths CEM, Ashcroft DM. National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study. BMJ 2020; 369: m1590.

https://doi.org/10.1136/bmj.m1590 DOI: https://doi.org/10.1136/bmj.m1590

Modalsli EH, Snekvik I, Asvold BO, Romundstad PR, Naldi L, Saunes M. Validity of self-reported psoriasis in a general population: the HUNT Study, Norway. J Invest Dermatol 2016; 136: 323-325.

https://doi.org/10.1038/JID.2015.386 DOI: https://doi.org/10.1038/JID.2015.386

Danielsen K, Olsen AO, Wilsgaard T, Furberg AS. Is the prevalence of psoriasis increasing? A 30-year follow-up of a population-based cohort. Br J Dermatol 2013; 168: 1303-1310.

https://doi.org/10.1111/bjd.12230 DOI: https://doi.org/10.1111/bjd.12230

Elmets CA, Leonardi CL, Davis DMR, Gelfand JM, Lichten J, Mehta NN, et al. Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with awareness and attention to comorbidities. J Am Acad Dermatol 2019; 80: 1073-1113.

https://doi.org/10.1016/j.jaad.2018.11.058 DOI: https://doi.org/10.1016/j.jaad.2018.11.058

Blake T, Gullick NJ, Hutchinson CE, Barber TM. Psoriatic disease and body composition: a systematic review and narrative synthesis. PloS One 2020; 15: e0237598-e0237598.

https://doi.org/10.1371/journal.pone.0237598 DOI: https://doi.org/10.1371/journal.pone.0237598

Douroudis K, Ramessur R, Barbosa IA, Baudry D, Duckworth M, Angit C, et al. Differences in clinical features and comorbid burden between HLA-C*06:02 carrier groups in >9,000 people with psoriasis. J Invest Dermatol 2022; 142: 1617-1628.e1610.

https://doi.org/10.26226/morressier.61081ff8bc981037240fe3af DOI: https://doi.org/10.26226/morressier.61081ff8bc981037240fe3af

Dand N, Duckworth M, Baudry D, Russell A, Curtis CJ, Lee SH, et al. HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis. J Allergy Clin Immunol 2019; 143: 2120-2130.

https://doi.org/10.1016/j.jaci.2018.11.038 DOI: https://doi.org/10.1016/j.jaci.2018.11.038

Svedbom A, Mallbris L, Larsson P, Nikamo P, Wolk K, Kjellman P, et al. Long-term outcomes and prognosis in new-onset psoriasis. JAMA Dermatol 2021; 157: 684-690.

https://doi.org/10.1001/jamadermatol.2021.0734 DOI: https://doi.org/10.1001/jamadermatol.2021.0734

Åsvold BO, Langhammer A, Rehn TA, Kjelvik G, Grøntvedt TV, Sørgjerd EP, et al. Cohort profile update: the HUNT study, Norway. Int J Epidemiol 2023; 52: e80-e91.

https://doi.org/10.1093/ije/dyac095 DOI: https://doi.org/10.1093/ije/dyac095

Brumpton BM, Graham S, Surakka I, Skogholt AH, Løset M, Fritsche LG, et al. The HUNT study: a population- based cohort for genetic research. Cell Genomics 2022; 2: 100193.

https://doi.org/10.1016/j.xgen.2022.100193 DOI: https://doi.org/10.1016/j.xgen.2022.100193

Hao Y, Zhu Y-j, Zou S, Zhou P, Hu Y-w, Zhao Q-x, et al. Metabolic syndrome and psoriasis: mechanisms and future directions. Front Immunol 2021; 12: 711060.

https://doi.org/10.3389/fimmu.2021.711060 DOI: https://doi.org/10.3389/fimmu.2021.711060

Enos CW, Ramos VL, McLean RR, Lin T-C, Foster N, Dube B, et al. Comorbid obesity and history of diabetes are independently associated with poorer treatment response to biologics at 6 months: a prospective analysis in Corrona Psoriasis Registry. J Am Acad Dermatol 2022; 86: 68-76.

https://doi.org/10.1016/j.jaad.2021.06.883 DOI: https://doi.org/10.1016/j.jaad.2021.06.883

Published

2023-05-05

How to Cite

Solvin, Åshild Øksnevad, Bjarkø, V. V., Thomas, L. F., Berrospi, P., Hveem, K., Saunes, M., Åsvold, B. O., & Løset, M. (2023). Body Composition, Cardiometabolic Risk Factors and Comorbidities in Psoriasis and the Effect of HLA-C*06:02 Status: The HUNT Study, Norway. Acta Dermato-Venereologica, 103, adv5209. https://doi.org/10.2340/actadv.v103.5209