Spironolactone and cimetidine in treatment of acne
DOI:
https://doi.org/10.2340/00015555688487Abstract
In an open therapeutic trial, 50 patients with acne vulgaris were randomly allocated to one of two groups. One group received spironolactone 100 mg daily and the other cimetidine 1.6 g daily for 12 weeks. Clinical severity of acne and sebum excretion decreased significantly at the end of the trial with both drugs, but significantly more with spironolactone. Mean serum levels of testosterone, androstenedione and dehydroepiandrosterone-sulfate decreased significantly with spironolactone but showed no change with cimetidine. Our data suggest that spironolactone may be useful as antiandrogen in the short term therapy of acne vulgaris.Downloads
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Published
1988-01-01
How to Cite
Hatwal, A., Bhatt, R., Agrawal, J., Singh, G., & Bajpai, H. (1988). Spironolactone and cimetidine in treatment of acne. Acta Dermato-Venereologica, 68(1), 84–87. https://doi.org/10.2340/00015555688487
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Copyright (c) 1988 A Hatwal, RP Bhatt, JK Agrawal, G Singh, HS. BajpaiAll digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.
Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.
