Effects of retinoids on type IV collagenolytic activity in melanoma cells
DOI:
https://doi.org/10.2340/0001555566346348Abstract
The effects of retinol, all-trans-retinoic acid, isotretinoin and etretinate on the activity of basement membrane collagen degrading enzyme was studied in melanoma cells. The results indicated that retinoids at concentrations of up to 10(-6) M did not significantly affect type IV collagenolytic activity in these cells in vitro. Since type IV collagenolytic enzyme may be involved in the metastatic potential of tumour cells, it appears that retinoids do not affect the metastatic potential of melanoma cells by affecting type IV collagenolytic activity.Downloads
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Published
1986-07-01
How to Cite
Oikarinen, A., & Salo, T. (1986). Effects of retinoids on type IV collagenolytic activity in melanoma cells. Acta Dermato-Venereologica, 66(4), 346–348. https://doi.org/10.2340/0001555566346348
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Copyright (c) 1986 Acta Dermato-VenereologicaAll digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.
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