Response of multiple syringomas to isotretinoin
DOI:
https://doi.org/10.2340/00015555665155Abstract
Two female patients with multiple syringomas were treated for 5/6 months with cumulative doses of 9 and 11 g isotretinoin respectively. Clinically, the appearance of the lesions in both patients improved from the third month on. After therapy, the lesions were flattened, softened, and skin coloured. Histologically, a marked reduction of size and numbers of syringomas was observed, and the contents of cystic lesions seemed reduced 6 months after therapy. Ultrastructurally, changes in the cystic and ductal epithelium correspond with the keratin modulating efficacy of the drug, but also point at a drug-induced change in intracellular lipid composition.Downloads
Download data is not yet available.
Downloads
Published
1986-01-01
How to Cite
Mainitz, M., Schmidt, J., & Gebhart, W. (1986). Response of multiple syringomas to isotretinoin. Acta Dermato-Venereologica, 66(1), 51–55. https://doi.org/10.2340/00015555665155
Issue
Section
Articles
License
Copyright (c) 1986 Acta Dermato-VenereologicaAll digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.
Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.
