An immunohistochemical staining of epidermal Langerhans´ cells in tinea cruris

Authors

  • L Emtestam
  • T Kaaman
  • A Hovmark
  • E. Asbrink

DOI:

https://doi.org/10.2340/0001555565240243

Abstract

Epidermal Langerhans´ cells (LC) were investigated in fresh cryostat sections of ten biopsies from patients with mycologically proven tinea cruris, using OKT6 monoclonal antibodies and avidin-biotin-immunoperoxidase. Compared to the controls, more epidermal LC and an increased number of LC in the upper half of the epidermis were found in the sections from tinea patients. In a double staining method for both OKT6-positivity and hyphae, a tendency towards a gathering of LC and fungal elements was found. The results of this study are in agreement with the theory that epidermal LC are responsible for the antigen uptake in dermatophytosis.

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Published

1985-05-01

How to Cite

Emtestam, L., Kaaman, T., Hovmark, A., & Asbrink, E. (1985). An immunohistochemical staining of epidermal Langerhans´ cells in tinea cruris. Acta Dermato-Venereologica, 65(3), 240–243. https://doi.org/10.2340/0001555565240243

Issue

Vol. 65 No. 3 (1985)

Section

Articles

License

Copyright (c) 1985 Acta Dermato-Venereologica

All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.

Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.

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