HLA -A, -B, -C and -DR antigens in individuals with sensitivity to cobalt
DOI:
https://doi.org/10.2340/0001555564121124Abstract
In a skin investigation of 853 individuals working with hard metal manufacturing 39 cases of cobalt allergy were found. Thirty-five of the individuals with cobalt sensitivity and 102 matched controls were HLA-A, -B, -C and -DR typed. No significantly deviating HLA antigen frequencies were observed when the two groups were compared. Thus, there are no signs that a certain HLA antigen would dispose to cobalt allergy. In the cobalt sensitive group the B7 positive individuals showed particularly often simultaneous reactions to other contact allergens (p = less than 0.025). The B12 positive individuals had low reactivity (p = less than 0.0001) while the A28 positive showed high reactivity (p = less than 0.015).Downloads
Download data is not yet available.
Downloads
Published
1984-03-01
How to Cite
Fischer, T., Rystedt, I., Säfwenberg, J., & Egle, I. (1984). HLA -A, -B, -C and -DR antigens in individuals with sensitivity to cobalt. Acta Dermato-Venereologica, 64(2), 121–124. https://doi.org/10.2340/0001555564121124
Issue
Section
Articles
License
LicenseAll digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.
Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.
