Systemic Combination Treatment for Psoriasis: A Review

Authors

  • Peter Jensen
  • Lone Skov
  • Claus Zachariae

DOI:

https://doi.org/10.2340/00015555-0905

Keywords:

psoriasis, systemic treatment, combination treatment

Abstract

Psoriasis is a chronic inflammatory skin disease, which affects approximately 2.6% of the population in Northern Europe and Scandinavia. In order to achieve disease control, combinations of systemic treatments are sometimes needed for variable time periods. However, no evidence-based guidelines exist for the use of systemic combination therapy. Therefore, our aim was to review the current literature on systemic anti-psoriatic combination regimens. We searched PubMed and identified 98 papers describing 116 studies (23 randomized) reporting on the effect of various systemic combination treatments. The most thoroughly investigated combination was retinoid and phototherapy. Further controlled research is needed to define the safest and most effective combination regimens.

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Published

2010-06-03

How to Cite

Jensen, P., Skov, L., & Zachariae, C. (2010). Systemic Combination Treatment for Psoriasis: A Review. Acta Dermato-Venereologica, 90(4), 341–349. https://doi.org/10.2340/00015555-0905

Issue

Section

Review