Galactose tolerance test and methotrexate-induced liver fibrosis and cirrhosis in patients with psoriasis

Authors

  • P. Lenler-Petersen
  • H. Søgård
  • K. Thestrup-Pedersen
  • H. Zachariae

DOI:

https://doi.org/10.2340/0001555562448449

Abstract

A total of 151 galactose tolerance tests (GTT) and liver biopsies were performed in a consecutive study of 45 psoriatic patients with methotrexate-induced liver fibrosis; of these, 23 had cirrhosis. Most patients with an abnormal liver histology had a normal GTT. We conclude that an oral GTT is not sensitive enough to reveal methotrexate-induced liver fibrosis or cirrhosis. The results indicate that the histological changes in methotrexate-induced liver fibrosis and cirrhosis may be of a rather non-aggressive nature.

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Published

1982-09-20

How to Cite

Lenler-Petersen, P., Søgård, H., Thestrup-Pedersen, K., & Zachariae, H. (1982). Galactose tolerance test and methotrexate-induced liver fibrosis and cirrhosis in patients with psoriasis. Acta Dermato-Venereologica, 62(5), 448–449. https://doi.org/10.2340/0001555562448449

Issue

Section

Articles