Sustained CD19+CD27+ Memory B Cell Depletion after Rituximab Treatment in Patients with Pemphigus Vulgaris
DOI:
https://doi.org/10.2340/actadv.v102.907Keywords:
Pemphigus, Rituximab, Therapy, Immunosuppression, SARS-CoV2, COVID-19Abstract
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Kasperkiewicz M, Ellebrecht CT, Takahashi H, Yamagami J, Zillikens D, Payne AS, et al. Pemphigus. Nat Rev Dis Primers 2017; 3: 17026.
https://doi.org/10.1038/nrdp.2017.26
Schmidt E, Kasperkiewicz M, Joly P. Pemphigus. Lancet 2019; 394: 882-894.
https://doi.org/10.1016/S0140-6736(19)31778-7
Joly P, Horvath B, Patsatsi Α, Uzun S, Bech R, Beissert S, et al. Updated S2K guidelines on the management of pemphigus vulgaris and foliaceus initiated by the European Academy of Dermatology and Venereology (EADV). J Eur Acad Dermatol Venereol 2020; 34: 1900-1913.
https://doi.org/10.1111/jdv.16752
Joly P, Maho-Vaillant M, Prost-Squarcioni C, Hebert V, Houivet E, Calbo S, et al. First-line rituximab combined with short-term prednisone versus prednisone alone for the treatment of pemphigus (Ritux 3): a prospective, multicentre, parallel-group, open-label randomised trial. Lancet 2017; 389: 2031-2040.
https://doi.org/10.1016/S0140-6736(17)30070-3
Colliou N, Picard D, Caillot F, Calbo S, Le Corre S, Lim A, et al. Long-term remissions of severe pemphigus after rituximab therapy are associated with prolonged failure of desmoglein B cell response. Sci Transl Med 2013; 5: 175ra30.
https://doi.org/10.1126/scitranslmed.3005166
Thaunat O, Morelon E, Defrance T. Am"B"valent: Anti-CD20 antibodies unravel the dual role of B cells in immunopathogenesis. Blood 2010; 116: 515-521.
https://doi.org/10.1182/blood-2010-01-266668
Schmidt E, Goebeler M, Hertl M, Sárdy M, Sitaru C, Eming R, et al. S2k guideline for the diagnosis of pemphigus vulgaris/foliaceus and bullous pemphigoid. J Dtsch Dermatol Ges 2015; 13: 713-727.
https://doi.org/10.1111/ddg.12612
Daniel BS, Hertl M, Werth VP, Eming R, Murrell DF. Severity score indexes for blistering diseases. Clin Dermatol 2012; 30: 108-113.
https://doi.org/10.1016/j.clindermatol.2011.03.017
Isolation of mononuclear cells from human peripheral blood by density gradient centrifugation. [accessed 2022 Feb 14] Available from: https://www.miltenyibiotec.com/_Resources/Persistent/6d7e0fb8a3eab613958d142051e3c7050eb0c8a9/SP_MC_PB_density_gradient.pdf.
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Copyright (c) 2022 Katharina Boch; Ewan A. Langan; Enno Schmidt, Detlef Zillikens, Ralf J. Ludwig, Katja Bieber, Christoph M. Hammers

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