Detection of Human Herpesvirus 8 in the Skin of Patients with Pityriasis Rosea
DOI:
https://doi.org/10.2340/00015555-0703Keywords:
pityriasis rosea, human herpesvirus 8, pathogenesis, exanthema.Abstract
Pityriasis rosea is an acute self-limiting dermatosis with clinical and epidemiological features that suggest viral involvement. The aim of this study was to investigate a possible association between pityriasis rosea and human herpesvirus 8 (HHV-8). Lesional skin tissue was obtained from 34 Kaposi´s sarcoma-negative, immunocompetent patients with typical acute phase pityriasis rosea. Nested polymerase chain reaction with specific primer for HHV-8 DNA sequences was performed and all positive results were confirmed by sequencing. Seven out of 34 lesional skin specimens (20.5%) were found to be positive for the HHV-8 genome. All the positive samples were confirmed by DNA sequencing. We conclude that, in some cases, HHV-8 is implicated the pathogenesis of pityriasis rosea.Downloads
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Published
2009-08-28
How to Cite
Prantsidis, A., Rigopoulos, D., Papatheodorou, G., Menounos, P., StamatisGregoriou, Alexiou-Mousatou, I., & Katsambas, A. (2009). Detection of Human Herpesvirus 8 in the Skin of Patients with Pityriasis Rosea. Acta Dermato-Venereologica, 89(6), 604–606. https://doi.org/10.2340/00015555-0703
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