Cutaneous Adnexal Adenocarcinoma: Genomic Analysis and Successful HER2-targeted Therapy of Metastatic Disease

Authors

  • Yui Hirano-Lotman Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
  • Yoshihiro Ishida Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
  • Yuichiro Endo Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
  • Seishi Ogawa Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
  • Kenji Kabashima Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan

DOI:

https://doi.org/10.2340/actadv.v103.9399

Keywords:

adnexal adenocarcinoma, cutaneous adnexal adenocarcinoma, adnexal adenocarcinoma NOS, her2, whole genome sequencing, her-2 antibodies

Abstract

Abstract is missing (Short communication)

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References

De Iuliis F, Amoroso L, Taglieri L, Vendittozzi S, Blasi L, Salerno G, et al. Chemotherapy of rare skin adnexal tumors: a review of literature. Anticancer Res 2014; 34: 5263-5238

Swain SM, Miles D, Kim SB, Im YH, Im SA, Semiglazov V, et al. CLEOPATRA study group. Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA): end-of-study results from a double-blind, randomised, placebo-controlled, phase 3 study. Lancet Oncol 2020; 21: 519-530.

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Cavalieri S, Busico A, Capone I, Conca E, Dallera E, Quattrone P, et al. Identification of potentially druggable molecular alterations in skin adnexal malignancies. J Dermatol 2019; 46: 507-514.

https://doi.org/10.1111/1346-8138.14889 DOI: https://doi.org/10.1111/1346-8138.14889

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https://doi.org/10.1038/ng.3525 DOI: https://doi.org/10.1038/ng.3525

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https://doi.org/10.1117/1.2957970 DOI: https://doi.org/10.1117/1.2957970

Brown TJ, Sher DJ, Nedzi LA, Hughes RS, Beg MS, Mull J, et al. Cutaneous adnexal adenocarcinoma with exquisite sensitivity to trastuzumab. Head Neck 2017; 39: E69-71.

https://doi.org/10.1002/hed.24682 DOI: https://doi.org/10.1002/hed.24682

Otsuka M, Yamasaki O, Kaji T, Shien T, Iwatsuki K. Metastatic cutaneous apocrine adenocarcinoma treated with a combination of pertuzumab-based targeted therapy and taxane chemotherapy: a case report. JAMA Dermatol 2016; 152: 111-113.

https://doi.org/10.1001/jamadermatol.2015.2507 DOI: https://doi.org/10.1001/jamadermatol.2015.2507

Published

2023-08-16

How to Cite

Hirano-Lotman, Y., Ishida, Y., Endo, Y., Ogawa, S., & Kabashima, K. (2023). Cutaneous Adnexal Adenocarcinoma: Genomic Analysis and Successful HER2-targeted Therapy of Metastatic Disease. Acta Dermato-Venereologica, 103, adv9399. https://doi.org/10.2340/actadv.v103.9399

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