Anti-demineralization effect of desensitizer containing copolymer and sodium fluoride on root dentin – a transverse microradiographic study

Kazuaki Kawamura; Yuichi Kunimatsu; Takafumi Nakano; Haruhiko Hasegawa; Hirohisa Arakawa; Yoshiharu Mukai

doi:10.1080/23337931.2019.1591967

Authors

Kazuaki Kawamura Division of Oral Health, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, Yokosuka, Japan
Yuichi Kunimatsu Division of Restorative Dentistry, Department of Oral Interdisciplinary Medicine, Graduate School of Dentistry, Kanagawa Dental University, Yokosuka, Japan
Takafumi Nakano Division of Oral Health, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, Yokosuka, Japan
Haruhiko Hasegawa Division of Restorative Dentistry, Department of Oral Interdisciplinary Medicine, Graduate School of Dentistry, Kanagawa Dental University, Yokosuka, Japan
Hirohisa Arakawa Division of Oral Health, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, Yokosuka, Japan
Yoshiharu Mukai Division of Restorative Dentistry, Department of Oral Interdisciplinary Medicine, Graduate School of Dentistry, Kanagawa Dental University, Yokosuka, Japan

DOI:

https://doi.org/10.1080/23337931.2019.1591967

Keywords:

Fluoride, copolymer, desensitizer, demineralization

Abstract

Objective: To evaluate anti-demineralization effects of dentin desensitizer containing sodium fluoride and methacrylate-co-p-styrene sulfonic acid (MS polymer) on root dentin using transverse microradiography (TMR).

Material and methods: Twenty-four dentin specimens were divided into four groups: MSO (no fluoride), MSF (3000 ppm F), FJL (9000 ppm F), and Control. In MSO and MSF, each desensitizer was rubbed into the dentin surfaces for 10 s then left for 20 s. In FJL, paste containing 9000 ppm F was applied onto the surface for 30 s. All specimens, including the Controls, were rinsed with deionized water, dried and an area of their surface exposed to pH 5.0 acidic solution, refreshed every 24 h, for 4 days. Sections 300-µm-thick were assessed by TMR. Mineral profiles and integrated mineral loss (IML) of lesions were analyzed by dedicated software. IML was analyzed with one-way ANOVA and Tukey’s test.

Results: MSF and FJL specimens showed high mineral volume % at the surface and in lesions, and significantly lower IML than the other groups (p < .05).

Conclusion: Dentin desensitizer containing 3000 ppm fluoride and MS polymer has the same anti-demineralization effect as does a fluoride paste containing 9000 ppm F.