One year monitoring of calcium release from an experimental composite containing calcium phosphate particles
DOI:
https://doi.org/10.2340/biid.v12.44586Keywords:
Calcium orthophosphate, ion release, resin compositeAbstract
Introduction: Ca2+ release from specimens made of a composite containing dicalcium phosphate dihydrate particles (CaHPO4.2H2O, dicalcium phosphate dihydrate [DCPD]) was followed during 1 year.
Methods: Specimens were individually immersed in deionized water (n = 3). Every 2 weeks, immersion medium was collected and specimens were transferred to new vials with fresh medium. Ca2+ release was quantified using induced coupled plasma-optical emission spectrometry (ICP-OES). Data were analyzed by ANOVA/Tukey test (alpha: 5%).
Results: Ca2+ release was observed during the entire 12-month period. Cumulative release was 1635.1 ± 145.3 μg/cm2 (179.7 ± 16.0 ppm), corresponding to 23.8 ± 2.0% of the total Ca mass in the specimen.
Conclusion: The tested composite was capable of sustained Ca2+ release in water for 1 year. In spite of the limitations of this screening test, the results suggest that composites containing Calcium phosphate (CaP) particles could offer a long-term Ca2+ supply to the adjacent dental tissues.
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Copyright (c) 2025 Handially Vilela, Mariana Nakamura, Roberto Braga
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Biomaterial Investigations in Dentistry is a Diamond Open Access peer-reviewed journal, publishing research in oral biomaterials science. The publishing of articles is free for authors, thanks to the support of Acta Odontologica Scandinavica Society (AOSS), a not-for-profit society. 
