Delayed endodontic management of traumatically exposed immature maxillary anterior teeth: a case series
DOI:
https://doi.org/10.2340/biid.v13.45434Keywords:
Pulpotomy, apexogenesis, young teeth, complicated crown fracture, traumaAbstract
Background: Traumatic dental injuries are a leading cause of pulpal exposure in immature permanent anterior teeth. Vital pulp therapy (VPT), particularly pulpotomy, has become the preferred treatment modality in such cases as it maintains pulp function, supports physiologic dentin deposition, and promotes long-term tooth retention. However, treatment delays may compromise clinical outcomes due to bacterial contamination and progressive pulpal inflammation. Mineral trioxide aggregate (MTA) and Biodentine™, both hydraulic calcium silicate cements, have demonstrated favorable biological responses in VPT.
Aim: To evaluate clinical and radiographic outcomes of full pulpotomy using MTA and Biodentine™ in immature permanent teeth with complicated crown fractures and delayed treatment intervals of up to 10 days.
Methods: This case series included eight immature maxillary central incisors in seven patients, aged 8.5–9.5 years, presenting with complicated crown fractures. Full pulpotomy was performed using either MTA or Biodentine™ following standardized clinical protocols, and teeth were restored in the same visit, with fragment reattachment performed when feasible. Clinical and radiographic follow-up was conducted at 1 week and at 1, 3, 6, 12, 18, and 24 months.
Results: At 18–24 months, all treated teeth remained vital, demonstrated resolution of symptoms, and showed continued physiologic root development consistent with successful apexogenesis. A radiographic dentinal bridge was observed in three teeth. No cases exhibited pathological changes such as periapical radiolucency, swelling, or restoration failure, except for one case with crown discoloration.
Conclusion: Full pulpotomy using MTA or Biodentine™ may represent a promising treatment option for traumatically exposed immature permanent teeth, even when initiated up to 10 days after injury; however, these findings should be interpreted cautiously in view of the limited sample size and follow-up duration.
Downloads
References
Marinčák D, Doležel V, Přibyl M, Voborná I, Marek I, Šedý J, et al. Conservative Treatment of Complicated Crown Fracture and Crown-Root Fracture of Young Permanent Incisor—A Case Report with 24-Month Follow-Up. Children. 2021; 8(9):725. https://doi.org/10.3390/children8090725 DOI: https://doi.org/10.3390/children8090725
Ojeda-Gutierrez F, Martinez-Marquez B, Arteaga-Larios S, Ruiz-Rodriguez MS, Pozos-Guillen A. Management and followup of complicated crown fractures in young patients treated with partial pulpotomy. Case Rep Dent. 2013;2013:597563. https://doi.org/10.1155/2013/597563 DOI: https://doi.org/10.1155/2013/597563
Haikal L, Ferraz Dos Santos B, Vu DD, Braniste M, Dabbagh B. Biodentine™ pulpotomies on permanent traumatized teeth with complicated crown fractures. J Endod. 2020;46(9):1204–9. https://doi.org/10.1016/j.joen.2020.06.003 DOI: https://doi.org/10.1016/j.joen.2020.06.003
Koyuncuoglu G, Gorken FN, Ikikarakayali G, Zorlu S, Erdem AP, Sepet E, et al. Management of open apices in thirteen traumatized permanent incisors using mineral trioxide aggregate: case series. Pediatr Dent J. 2013;23:51–56. https://doi.org/10.1016/j.pdj.2013.03.007 DOI: https://doi.org/10.1016/j.pdj.2013.03.007
Abuelniel GM, Duggal MS, Kabel N. A comparison of MTA and Biodentine™ as medicaments for pulpotomy in traumatized anterior immature permanent teeth: a randomized clinical trial. Dent Traumatol. 2020;36(4):400–10. https://doi.org/10.1111/edt.12553 DOI: https://doi.org/10.1111/edt.12553
Donnelly A, Foschi F, McCabe P, Duncan HF. Pulpotomy for treatment of complicated crown fractures in permanent teeth: a systematic review. Int Endod J. 2022;55(4):290–311. https://doi.org/10.1111/iej.13690 DOI: https://doi.org/10.1111/iej.13690
Matoug-Elwerfelli M, ElSheshtawy AS, Duggal M, Tong HJ, Nazzal H. Vital pulp treatment for traumatized permanent teeth: a systematic review. Int Endod J. 2022;55(6):613–29. https://doi.org/10.1111/iej.13741 DOI: https://doi.org/10.1111/iej.13741
Klingberg G, Broberg AG. Dental fear/anxiety and dental behaviour management problems in children and adolescents: a review of prevalence and concomitant psychological factors. Int J Paediatr Dent. 2007;17(6):391–406. https://doi.org/10.1111/j.1365-263X.2007.00872.x DOI: https://doi.org/10.1111/j.1365-263X.2007.00872.x
American Academy of Pediatric Dentistry. Behavior guidance for the pediatric dental patient. The Reference Manual of Pediatric Dentistry. Chicago, IL: American Academy of Pediatric Dentistry; 2025:379-99
Kahler B, Rossi-Fedele G. A review of tooth fracture strength in immature teeth treated endodontically with mineral trioxide aggregate. Int Endod J. 2016;49(3):255–66.
Forghani M, Parisay I, Maghsoudlou A. Apexogenesis and revascularization treatment procedures for two traumatized immature permanent maxillary incisors: a case report. Restor Dent Endod. 2013;38:178–81. https://doi.org/10.5395/rde.2013.38.3.178 DOI: https://doi.org/10.5395/rde.2013.38.3.178
Mejàre I, Cvek M. Partial pulpotomy in young permanent teeth with deep carious lesions. Endod Dent Traumatol. 1993;9(6):238–42. https://doi.org/10.1111/j.1600-9657.1993.tb00279.x DOI: https://doi.org/10.1111/j.1600-9657.1993.tb00279.x
Bourguignon C, Cohenca N, Lauridsen E, Flores MT, O'Connell AC, Day PF, et al.International Association of Dental Traumatology guidelines for the management of traumatic dental injuries: 1. Fractures and luxations. Dent Traumatol. 2020 Aug;36(4):314-330. https://doi.org/10.1111/edt.12578. DOI: https://doi.org/10.1111/edt.12578
Wolters WJ, Duncan HF, Tomson PL, Karim IE, McKenna G, Dorri M, et al. Minimally invasive endodontics: a new diagnostic system for assessing pulpitis and subsequent treatment needs. Int Endod J. 2017;50(9):825–9. https://doi.org/10.1111/iej.12793 DOI: https://doi.org/10.1111/iej.12793
Camilleri J. Hydration characteristics of Biodentine and Theracal used as pulp capping materials. Dent Mater. 2014;30(7):709–15. https://doi.org/10.1016/j.dental.2014.03.012 DOI: https://doi.org/10.1016/j.dental.2014.03.012
Surekha GL, Vinay C, Baliga S, Uloopi KS, RojaRamya KS, Penmatsa C. Effect of preconditioning the fractured coronal fragments with remineralizing agents on fracture resistance of re-attached teeth. J Indian Soc Pedod Prev Dent. 2021;39(4):384–7. https://doi.org/10.4103/jisppd.jisppd_376_21 DOI: https://doi.org/10.4103/jisppd.jisppd_376_21
Jalannavar P, Tavargeri A. Influence of storage media and duration of fragment in the media on the bond strength of the reattached tooth fragment. Int J Clin Pediatr Dent. 2018;11(2):83–8. https://doi.org/10.5005/jp-journals-10005-1490 DOI: https://doi.org/10.5005/jp-journals-10005-1490
Ghorbanzadeh A, Ghorbanzadeh A. Maturogenesis of two maxillary central incisors: a case report with 10 years of follow up. J Dent (Tehran). 2015;12(4):306–15.
Robertson A, Andreasen FM, Andreasen JO, Norén JG. Long-term prognosis of crown-fractured permanent incisors. The effect of stage of root development and associated luxation injury. Int J Paediatr Dent. 2000;10(3):191–9. https://doi.org/10.1046/j.1365-263x.2000.00191.x DOI: https://doi.org/10.1046/j.1365-263x.2000.00191.x
da Rosa WLO, Piva E, da Silva AF. Disclosing the physiology of pulp tissue for vital pulp therapy. Int Endod J. 2018;51(8):829–46. https://doi.org/10.1111/iej.12906 DOI: https://doi.org/10.1111/iej.12906
Fatima S, Alam S, Kumar A, Andrabi SMUN, Rehman A. Minimal intervention treatment of crown-root fracture in a mature permanent tooth by MTA pulpotomy and fragment reattachment: a case report. Aust Endod J. 2021;47(2):365–71. https://doi.org/10.1111/aej.12477 DOI: https://doi.org/10.1111/aej.12477
Krastl G, Weiger R, Filippi A, Van Waes H, Ebeleseder K, Ree M, et al. Endodontic management of traumatized permanent teeth: a comprehensive review. Int Endod J. 2021;54(8):1221–45. https://doi.org/10.1111/iej.13508 DOI: https://doi.org/10.1111/iej.13508
Andreasen JO, Andreasen FM, Andersson L. Textbook and color atlas of traumatic injuries to the teeth. 5th ed. Hoboken, NJ: Wiley-Blackwell; 2018. DOI: https://doi.org/10.25241/stomaeduj.2019.6(4).bookreview.3
Cvek M. A clinical report on partial pulpotomy and capping with calcium hydroxide in permanent incisors with complicated crown fracture. J Endod. 1978;4(8):232–7. https://doi.org/10.1016/S0099-2399(78)80153-8 DOI: https://doi.org/10.1016/S0099-2399(78)80153-8
Fuks AB, Cosack A, Klein H, Eidelman E. Partial pulpotomy as a treatment alternative for exposed pulps in crown-fractured permanent incisors. Endod Dent Traumatol. 1987;3(3):100–2. https://doi.org/10.1111/j.1600-9657.1987.tb00610.x DOI: https://doi.org/10.1111/j.1600-9657.1987.tb00610.x
Fuks AB, Gavra S, Chosack A. Long-term followup of traumatized incisors treated by partial pulpotomy. Pediatr Dent. 1993;15(5):334–6.
Fuks AB, Bielak S, Chosak A. Clinical and radiographic assessment of direct pulp capping and pulpotomy in young permanent teeth. Pediatr Dent. 1982;4(3):240–4.
Gelbier MJ, Winter GB. Traumatised incisors treated by vital pulpotomy: a retrospective study. Br Dent J. 1988;164(10):319–23. https://doi.org/10.1038/sj.bdj.4806440 DOI: https://doi.org/10.1038/sj.bdj.4806440
Hecova H, Tzigkounakis V, Merglova V, Netolicky J. A retrospective study of 889 injured permanent teeth. Dent Traumatol. 2010;26(6):466–75. https://doi.org/10.1111/j.1600-9657.2010.00924.x DOI: https://doi.org/10.1111/j.1600-9657.2010.00924.x
de Blanco LP. Treatment of crown fractures with pulp exposure. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996;82(5):564–8. https://doi.org/10.1016/s1079-2104(96)80204-6 DOI: https://doi.org/10.1016/S1079-2104(96)80204-6
Rao Q, Kuang J, Mao C, Dai J, Hu L, Lei Z, et al. Comparison of iRoot BP plus and calcium hydroxide as pulpotomy materials in permanent incisors with complicated crown fractures: a retrospective study. J Endod. 2020;46(3):352–7. https://doi.org/10.1016/j.joen.2019.12.010 DOI: https://doi.org/10.1016/j.joen.2019.12.010
Yu CY, Abbott PV. Responses of the pulp, periradicular and soft tissues following trauma to the permanent teeth. Aust Dent J. 2016;61 Suppl 1:39–58. https://doi.org/10.1111/adj.12397 DOI: https://doi.org/10.1111/adj.12397
Andreasen JO, Andreasen FM, Skeie A, Hjørting-Hansen E, Schwartz O. Effect of treatment delay upon pulp and periodontal healing of traumatic dental injuries – a review article. Dent Traumatol. 2002;18(3):116–28. https://doi.org/10.1034/j.1600-9657.2002.00079.x DOI: https://doi.org/10.1034/j.1600-9657.2002.00079.x
Shahmohammadi R, Sheikhnezami M, Moradi S, Jafarzadeh H, Azarpazhooh A. treatment outcomes of permanent immature teeth with crown fracture: a retrospective cohort study. J Endod. 2021;47(11):1715–23. https://doi.org/10.1016/j.joen.2021.08.010 DOI: https://doi.org/10.1016/j.joen.2021.08.010
Tzanetakis GN, Tsiouma O, Mougiou E, Koletsi D. Factors related to pulp survival after complicated crown fracture following vital pulp therapy: a systematic review and meta-analysis. J Endod. 2022;48(4):457–78.e4. https://doi.org/10.1016/j.joen.2022.01.013 DOI: https://doi.org/10.1016/j.joen.2022.01.013
Nosrat A, Asgary S. Apexogenesis treatment with a new endodontic cement: a case report. J Endod. 2010;36(5):912–4. https://doi.org/10.1016/j.joen.2009.11.025 DOI: https://doi.org/10.1016/j.joen.2009.11.025
Tran XV, Gorin C, Willig C, Baroukh B, Pellat B, Decup F, et al. Effect of a calcium silicate-based restorative cement on pulp repair. J Dent Res. 2012;91(12):1166–71. https://doi.org/10.1177/0022034512460833 DOI: https://doi.org/10.1177/0022034512460833
Caprioglio A, Conti V, Caprioglio C, Caprioglio D. A long-term retrospective clinical study on MTA pulpotomies in immature permanent incisors with complicated crown fractures. Eur J Paediatr Dent. 2014;15(1):29–34.
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Vignesh Ravi, Ruchi Singhal, Madhur Sharma, Ritu Namdev

This work is licensed under a Creative Commons Attribution 4.0 International License.
Biomaterial Investigations in Dentistry is a Diamond Open Access peer-reviewed journal, publishing research in oral biomaterials science. The publishing of articles is free for authors, thanks to the support of Acta Odontologica Scandinavica Society (AOSS), a not-for-profit society. 
