Blisters and Crusts on the Dorsum of the Hands: A Quiz


  • Benjamin Klein Department of Dermatology, Venereology and Allergology, University Medical Center Leipzig, DE-04103 Leipzig, Germany
  • Jan Christoph Simon
  • Konstantin Dumann
  • Regina Treudler



Abstract is missing (Quiz)


Download data is not yet available.


Bissell DM, Anderson KE, Bonkovsky HL. Porphyria. N Engl J Med 2017; 377: 862–872.

Handler NS, Handler MZ, Stephany MP, Handler GA, Schwartz RA. Porphyria cutanea tarda: an intriguing genetic disease and marker. Int J Dermatol 2017; 56: e106–e117.

Sarkany RPE. Making sense of the porphyrias. Photodermatol Photoimmunol Photomed 2008; 24: 102–108.

Vieira FMJ, Aoki V, De Oliveira ZNP, Martins JEC. Study of direct immunofluorescence, immunofluorescence mapping and light microscopy in porphyria cutanea tarda. An Bras Dermatol 2010; 85: 827–837.

Lim HW, Poh-Fitzpatrick MB, Gigli I. Activation of the complement system in patients with porphyrias after irradiation in vivo. J Clin Invest 1984; 74: 1961–1965.

De Groot HJ, Jonkman MF, Pas HH, Diercks GFH. Direct immunofluorescence of mechanobullous epidermolysis bullosa acquisita, porphyria cutanea tarda and pseudoporphyria. Acta Derm Venereol 2019; 99: 26–32.

Weidner T, Tittelbach J, Schliemann S, Goetze S, Elsner P. Blisters, ulcers, crusts, and atrophic scars on the back of the hands and the extensor aspects of the forearms. J Dtsch Dermatol Ges 2018; 16: 88–91.

Tintle S, Alikhan A, Horner ME, Hand JL, Davis DMR. Cutaneous porphyrias part II: Treatment strategies. Int J Dermatol 2014; 53: 3–24.

Tong Y, Song YK, Tyring S. Resolution of porphyria cutanea tarda in patients with hepatitis C following ledipasvir-sofosbuvir combination therapy. JAMA Dermatol 2016; 152: 1393–1395.

Christiansen AL, Brock A, Bygum A, Rasmussen LM, Jepsen P. Increased mortality in patients with porphyria cutanea tarda – a nationwide cohort study. J Am Acad Dermatol 2020; 83: 817–823.



How to Cite

Klein, B., Simon, J. C., Dumann, K., & Treudler, R. (2021). Blisters and Crusts on the Dorsum of the Hands: A Quiz. Acta Dermato-Venereologica, 101(8), adv00533.