First Use of Tapinarof Monotherapy for Seborrhoeic Dermatitis: A Case Report

Authors

  • Naiem T. Issa Issa Research and Consulting, LLC, Springfield, VA
  • Michael Kaiser Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine Dr. Phillip Frost, Miami, USA

DOI:

https://doi.org/10.2340/actadv.v103.12343

Keywords:

Seborrheic Dermatitis, Tapinarof

Abstract

Abstract is missing (Short communication)

Downloads

Download data is not yet available.

References

Szepietowski JC, Reich A, Wesołowska-Szepietowska E, Baran E, Group NQoLiD. Quality of life in patients suffering from seborrheic dermatitis: influence of age, gender and education level. Mycoses 2009; 52: 357-363.

https://doi.org/10.1111/j.1439-0507.2008.01624.x DOI: https://doi.org/10.1111/j.1439-0507.2008.01624.x

Jackson JM, Alexis A, Zirwas M, Taylor S. Unmet needs for patients with seborrheic dermatitis. J Am Acad Dermatol 2022 Dec 17 [Online ahead of print].

https://doi.org/10.1016/j.jaad.2022.12.017 DOI: https://doi.org/10.1016/j.jaad.2022.12.017

Borda LJ, Wikramanayake TC. Seborrheic dermatitis and dandruff: a comprehensive review. J Clin Investig Dermatol 2015; 3: 10.13188/2373-1044.1000019.

https://doi.org/10.13188/2373-1044.1000019 DOI: https://doi.org/10.13188/2373-1044.1000019

Keam SJ. Tapinarof cream 1%: first approval. Drugs 2022; 82: 1221-1228.

https://doi.org/10.1007/s40265-022-01748-6 DOI: https://doi.org/10.1007/s40265-022-01748-6

Adalsteinsson JA, Kaushik S, Muzumdar S, Guttman-Yassky E, Ungar J. An update on the microbiology, immunology and genetics of seborrheic dermatitis. Exp Dermatol 2020; 29: 481-489.

https://doi.org/10.1111/exd.14091 DOI: https://doi.org/10.1111/exd.14091

Gary G. Optimizing treatment approaches in seborrheic dermatitis. J Clin Aesthet Dermatol 2013; 6: 44.

Kastarinen H, Okokon EO, Verbeek JH. Topical anti-inflammatory agents for seborrheic dermatitis of the face or scalp: summary of a Cochrane Review. JAMA Dermatol 2015; 151: 221-222.

https://doi.org/10.1001/jamadermatol.2014.3186 DOI: https://doi.org/10.1001/jamadermatol.2014.3186

Nogueira S, Rodrigues MA, Vender R, Torres T. Tapinarof for the treatment of psoriasis. Dermatol Ther 2022; 35: e15931.

https://doi.org/10.1111/dth.15931 DOI: https://doi.org/10.1111/dth.15931

Uppal SK, Chat VS, Kearns DG, Wu JJ. Topical agents currently in phase II or phase III trials for atopic dermatitis. J Drugs Dermatol 2020; 19: 956-959.

https://doi.org/10.36849/JDD.2020.5214 DOI: https://doi.org/10.36849/JDD.2020.5214

Smith SH, Jayawickreme C, Rickard DJ, Nicodeme E, Bui T, Simmons C, et al. Tapinarof is a natural AhR agonist that resolves skin inflammation in mice and humans. J Invest Dermatol 2017; 137: 2110-2119.

https://doi.org/10.1016/j.jid.2017.05.004 DOI: https://doi.org/10.1016/j.jid.2017.05.004

Sutter CH, Azim S, Wang A, Bhuju J, Simpson AS, Uberoi A, et al. Ligand-activation of the aryl hydrocarbon receptor up-regulates epidermal UDP-glucose ceramide glucosyltransferase and glucosylceramides. J Invest Dermatol 2023 Mar 31 [online ahead of print].

https://doi.org/10.1016/j.jid.2023.03.1662 DOI: https://doi.org/10.1016/j.jid.2023.03.1662

Sekhon S, Koo J. Indirubin: a novel topical agent in the treatment of psoriasis. Br J Dermatol 2018; 178: 21-21.

https://doi.org/10.1111/bjd.16074 DOI: https://doi.org/10.1111/bjd.16074

Magiatis P, Pappas P, Gaitanis G, Mexia N, Melliou E, Galanou M, et al. Malassezia yeasts produce a collection of exceptionally potent activators of the Ah (dioxin) receptor detected in diseased human skin. J Invest Dermatol 2013; 133: 2023-2030.

https://doi.org/10.1038/jid.2013.92 DOI: https://doi.org/10.1038/jid.2013.92

Park HB, Goddard TN, Oh J, Patel J, Wei Z, Perez CE, et al. Bacterial autoimmune drug metabolism transforms an immunomodulator into structurally and functionally divergent antibiotics. Angewandte Chemie 2020; 132: 7945-7954.

https://doi.org/10.1002/ange.201916204 DOI: https://doi.org/10.1002/ange.201916204

Published

2023-06-27

How to Cite

Issa, N. T., & Kaiser, M. (2023). First Use of Tapinarof Monotherapy for Seborrhoeic Dermatitis: A Case Report. Acta Dermato-Venereologica, 103, adv12343. https://doi.org/10.2340/actadv.v103.12343