Herpes simplex virus infection in a hyper-IgE patient: appearance of unusual mass lesions
DOI:
https://doi.org/10.1080/00015550260132514Abstract
A 7-year-old girl presented with large soft masses rising from the nostril and from behind the ear. She had previously been diagnosed as suffering from hyper-IgE syndrome. The presence of herpes simplex virus infection within these lesions was confirmed by biopsy and immunohistochemical studies. The mass lesions did not respond to antibacterial therapy with cefazolin, but improved promptly under antiviral therapy with acyclovir. Immunological studies revealed a mild decrease in the CD4 cell population. Based on our results and on the relevant literature we propose an immunological mechanism for this unique manifestation of herpes simplex virus infection in hyper-IgE syndrome.Downloads
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Published
2002-10-02
How to Cite
Hershko, K., Hershko, A. Y., Leibovici, V., Meir, K., & Ingber, A. (2002). Herpes simplex virus infection in a hyper-IgE patient: appearance of unusual mass lesions. Acta Dermato-Venereologica, 82(3), 204–205. https://doi.org/10.1080/00015550260132514
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