Upregulation of RANTES in Psoriatic Keratinocytes: a Possible Pathogenic Mechanism for Psoriasis
DOI:
https://doi.org/10.1080/000155599750011615Abstract
Intraepidermal collections of neutrophils and lymphocytes are unique features of the inflammatory reaction of psoriasis. Migration of leukocytes from dermis to the epidermis suggests a role for chemotactic agent(s). In recent years, increased levels of chemokines such as IL-8 , GRO-a and MCP-1 have been reported in the keratinocytes of psoriatic tissue. IL-8 and GRO-alpha belong to a subfamily (C x C) class and MCP-1 is a beta chemokine. In this study, we investigated RANTES, which is a beta chemokine (C-C class)Downloads
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Published
1999-01-01
How to Cite
Raychaudhuri, S. P., Jiang, W.-Y., Farber, E. M., Schall, T. J., Ruff, M. R., & Pert, C. B. (1999). Upregulation of RANTES in Psoriatic Keratinocytes: a Possible Pathogenic Mechanism for Psoriasis. Acta Dermato-Venereologica, 79(1), 9–11. https://doi.org/10.1080/000155599750011615
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