Adult Acne in Middle-age: Effects on Mental Health in General Population of the Northern Finland Birth Cohort 1966
DOI:
https://doi.org/10.2340/actadv.v104.14733Keywords:
adult acne, mental health, depression, psychological, birth cohortAbstract
The impact of adult acne on patients’ mental health has not been widely studied, and most studies have been conducted within specific patient populations. The current study examines the association between adult acne and psychological symptoms in the Northern Finland Birth Cohort 1966 (NFBC1966) (n = 1,907). The cohort members attended a health study at the age of 46 years, which comprised a whole-body examination performed by dermatologists to identify acne, and answering the Beck Depression Inventory II (BDI-II), Athens Insomnia Scale (AIS), Generalized Anxiety Disorder (GAD-7), State-Trait Anxiety Inventory (STAI) and 15-dimensional measure of health-related quality of life (15D HRQoL) questionnaires. The prevalence of adult acne was 7.9% (n = 150) with no statistical differences between the sexes. Cases with acne presented more (18.9%) depressive symptoms (BDI-II > 14 points) compared with those without acne (9.7%) (p < 0.001). In adjusted logistic regression analyses, those with acne had a 2-fold risk (odds ratio (OR) 2.08, 95% confidence interval (95% CI) 1.23–3.38) of having depressive symptoms compared with controls. In conclusion, when treating adult acne patients, it is important to recognize the increased risk of mental health symptoms.
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References
Williams HC, Dellavalle RP, Garner S. Acne vulgaris. The Lancet 2012; 379: 361-372.
https://doi.org/10.1016/S0140-6736(11)60321-8 DOI: https://doi.org/10.1016/S0140-6736(11)60321-8
White GM. Recent findings in the epidemiologic evidence, classification, and subtypes of acne vulgaris. J Am Acad Dermatol 1998; 39: 34.
https://doi.org/10.1016/S0190-9622(98)70442-6 DOI: https://doi.org/10.1016/S0190-9622(98)70442-6
Shen Y, Wang T, Zhou C, Wang X, Ding X, Tian S, et al. Prevalence of acne vulgaris in Chinese adolescents and adults: a community-based study of 17,345 subjects in six cities. Acta Derm Venereol 2012; 92: 40-4.
https://doi.org/10.2340/00015555-1164 DOI: https://doi.org/10.2340/00015555-1164
Sinikumpu SP, Jokelainen J, Tasanen K, Huilaja L. Cardiovascular and metabolic profile in subjects with adult acne at the age of 46 years: a general population study of 1932 subjects. Acta Derm Venereol 2023; 103: adv5921.
https://doi.org/10.2340/actadv.v103.5921 DOI: https://doi.org/10.2340/actadv.v103.5921
Skroza N, Tolino E, Mambrin A, Zuber S, Balduzzi V, Marchesiello A, et al. Adult acne versus adolescent acne: a retrospective study of 1,167 patients. J Clin Aesthet Dermatol 2018; 11: 21-25.
Samuels D V., Rosenthal R, Lin R, Chaudhari S, Natsuaki MN. Acne vulgaris and risk of depression and anxiety: a meta-analytic review. J Am Acad Dermatol 2020; 83: 532-541.
https://doi.org/10.1016/j.jaad.2020.02.040 DOI: https://doi.org/10.1016/j.jaad.2020.02.040
Altunay İK, Özkur E, Dalgard FJ, Gieler U, Tomas-Aragones L, Lien L, et al. Psychosocial aspects of adult acne: data from 13 European countries. Acta Derm Venereol 2020; 100: 1-6.
https://doi.org/10.2340/00015555-3409 DOI: https://doi.org/10.2340/00015555-3409
Tanghetti EA, Kawata AK, Daniels SR, Yeomans K, Burk CT, Callender VD. Understanding the burden of adult female acne. J Clin Aesthet Dermatol 2014; 7: 22-30.
Henkel V, Mœhrenschlager M, Hegerl U, Mœller HJ, Ring J, Worret WI. Screening for depression in adult acne vulgaris patients: tools for the dermatologist. J Cosmet Dermatol 2002; 1: 202-207.
https://doi.org/10.1111/j.1473-2165.2002.00057.x DOI: https://doi.org/10.1111/j.1473-2165.2002.00057.x
Gül AI, Çölgeçen E. Personality traits and common psychiatric conditions in adult patients with acne vulgaris. Ann Dermatol 2015; 27: 48-52.
https://doi.org/10.5021/ad.2015.27.1.48 DOI: https://doi.org/10.5021/ad.2015.27.1.48
Rantakallio P. Groups at risk in low birth weight infants and perinatal mortality. Acta Paediatrica Scandinavia 1969; 193: 1-71.
University of Oulu. University of Oulu: Northern Finland Birth Cohort 1966. University of Oulu. University of Oulu: Northern Finland Birth Cohort 1966. University of Oulu. http://urn.fi/urn:nbn:fi:att:bc1e5408-980e-4a62-b899-43bec3755243.
Nordström T, Auvinen J, Ala-Mursula L, Keinänen-Kiukaanniemi S, Veijola J, Järvelin MR et al. Cohort profile: 46 years of follow-up of the Northern Finland Birth Cohort 1966 (NFBC1966). Int J Epidemiol 2022; 50: 1786-1787j.
https://doi.org/10.1093/ije/dyab109 DOI: https://doi.org/10.1093/ije/dyab109
Sinikumpu S-P, Huilaja L, Jokelainen J, Koiranen M, Auvinen J, Hägg PM, et al. High prevalence of skin diseases and need for treatment in a middle-aged population. a northern Finland birth cohort 1966 study. PLoS One 2014; 9: e99533.
https://doi.org/10.1371/journal.pone.0099533 DOI: https://doi.org/10.1371/journal.pone.0099533
Sinikumpu SP, Jokelainen J, Tasanen K, Timonen M, Huilaja L. Association between pruritus and psychosocial well-being: a population-based study among 6,809 subjects. Acta Derm Venereol 2023; 103: adv00837.
https://doi.org/10.2340/actadv.v103.2922 DOI: https://doi.org/10.2340/actadv.v103.2922
Winkleby MA, Jatulis DE, Frank E, Fortmann SP. Socioeconomic status and health: how education, income, and occupation contribute to risk factors for cardiovascular disease. Am J Public Health 1992; 82: 816-820.
https://doi.org/10.2105/AJPH.82.6.816 DOI: https://doi.org/10.2105/AJPH.82.6.816
Davidson KM. Diagnosis of depression in alcohol dependence: changes in prevalence with drinking status. Br J Psychiatry 1995; 166: 199-204.
https://doi.org/10.1192/bjp.166.2.199 DOI: https://doi.org/10.1192/bjp.166.2.199
Opel N, Redlich R, Grotegerd D, Dohm K, Heindel W, Kugel H, et al. Obesity and major depression: Body-mass index (BMI) is associated with a severe course of disease and specific neurostructural alterations. Psychoneuroendocrinology 2015; 51: 219-226.
https://doi.org/10.1016/j.psyneuen.2014.10.001 DOI: https://doi.org/10.1016/j.psyneuen.2014.10.001
Rebar AL, Stanton R, Geard D, Short C, Duncan MJ, Vandelanotte C. A meta-meta-analysis of the effect of physical activity on depression and anxiety in non-clinical adult populations. Health Psychol Rev 2015; 9: 366-378.
https://doi.org/10.1080/17437199.2015.1022901 DOI: https://doi.org/10.1080/17437199.2015.1022901
Fluharty M, Taylor AE, Grabski M, Munafo MR. The association of cigarette smoking with depression and anxiety: a systematic review. Nicotine Tob Res 2017; 19: 3-13.
https://doi.org/10.1093/ntr/ntw140 DOI: https://doi.org/10.1093/ntr/ntw140
Domenech-Abella J, Mundo J, Leonardi M, Chatterji S, Tobiasz-Adamczyk B, Koskinen S, et al. The association between socioeconomic status and depression among older adults in Finland, Poland and Spain: a comparative cross-sectional study of distinct measures and pathways. J Affect Disord 2018; 241: 311-318.
https://doi.org/10.1016/j.jad.2018.08.077 DOI: https://doi.org/10.1016/j.jad.2018.08.077
Cardwell LA, Farhangian ME, Alinia H, Kuo S, Feldman SR. Psychological disorders associated with rosacea: analysis of unscripted comments. J Dermatol Dermatologic Surg 2015; 19: 99-103.
https://doi.org/10.1016/j.jdds.2015.04.003 DOI: https://doi.org/10.1016/j.jdds.2015.04.003
Dumont-Wallon G, Dréno B. Specificity of acne in women older than 25 years. Presse Med 2008; 37: 585-591.
https://doi.org/10.1016/j.lpm.2007.07.014 DOI: https://doi.org/10.1016/j.lpm.2007.07.014
Collier CN, Harper JC, Cantrell WC, Wang W, Foster KW, Elewski BE. The prevalence of acne in adults 20 years and older. J Am Acad Dermatol 2008; 58: 56-59.
https://doi.org/10.1016/j.jaad.2007.06.045 DOI: https://doi.org/10.1016/j.jaad.2007.06.045
Kroza N, Tolino E, Proietti I, Bernardini N, La Viola G, Nicolucci F et al. Women and acne: any difference from males? A review of the literature. G Ital Dermatol Venereol 2016; 151: 87-92.
Dreno B, Bagatin E, Blume-Peytavi U, Rocha M, Gollnick H. Female type of adult acne: Physiological and psychological considerations and management. J Dtsch Dermatol Ges 2018; 16: 1185-1194.
https://doi.org/10.1111/ddg.13664 DOI: https://doi.org/10.1111/ddg.13664
Knaggs HE, Wood EJ, Rizer RL, Mills OH. Post-adolescent acne. Int J Cosmet Sci 2004; 26: 129-138.
https://doi.org/10.1111/j.1467-2494.2004.00210.x DOI: https://doi.org/10.1111/j.1467-2494.2004.00210.x
Rocha MA, Bagatin E. Adult-onset acne: prevalence, impact, and management challenges. Clin Cosmet Investig Dermatol 2018; 11: 59-69.
https://doi.org/10.2147/CCID.S137794 DOI: https://doi.org/10.2147/CCID.S137794
Mindell JS, Giampaoli S, Goesswald A, Kamtsiuris P, Mann C, Mannisto S, et al. Sample selection, recruitment and participation rates in health examination surveys in Europe - experience from seven national surveys. BMC Med Res Methodol 2015; 15: 74-78.
https://doi.org/10.1186/s12874-015-0072-4 DOI: https://doi.org/10.1186/s12874-015-0072-4
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