Pityrosporum ovale extracts increase interleukin-4, interleukin-10 and IgE synthesis in patients with atopic eczema.

Authors

  • S Kröger
  • K Neuber
  • E Gruseck
  • J Ring
  • D Abeck

DOI:

https://doi.org/10.2340/0001555575357360

Abstract

Evidence for a possible role of the lipophilic yeast Pityrosporum ovale in the pathophysiology of atopic eczema has been found both in laboratory and therapeutical studies. Positive type I prick test reactions to P. ovale correlate with the intensity of eczematous skin lesions in the head and neck regions of patients with atopic eczema. Furthermore, antifungal treatment has been shown to be helpful in atopic eczema. In the present study the effect of P. ovale on IgE synthesis and cytokine production (IL-2, IFN gamma, IL-4, IL-10) was investigated in patients with atopic eczema, in vitro. Eight patients with atopic eczema were studied

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Published

1995-09-01

How to Cite

Kröger, S., Neuber, K., Gruseck, E., Ring, J., & Abeck, D. (1995). Pityrosporum ovale extracts increase interleukin-4, interleukin-10 and IgE synthesis in patients with atopic eczema. Acta Dermato-Venereologica, 75(5), 357–360. https://doi.org/10.2340/0001555575357360

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Section

Articles