Involvement of Sensory Neurone-TRPV4 in Acute and Chronic Itch Behaviours

Authors

  • Qiaojuan Zhang
  • Fabiana Dias
  • Quan Fang
  • Gwendolyn Henry
  • Zilong Wang
  • Abbie Suttle
  • Yong Chen Dedpartment of Neurology, Duke University, Durham, NC 27710, USA

DOI:

https://doi.org/10.2340/actadv.v102.1621

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References

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https://doi.org/10.1016/j.alit.2016.10.003

Moore C, Gupta R, Jordt SE, Chen Y, Liedtke WB. Regulation of pain and itch by TRP channels. Neurosci Bull 2018; 34: 120-142.

https://doi.org/10.1007/s12264-017-0200-8

Sun S, Dong X. Trp channels and itch. Semin Immunopathol 2016; 38: 293-307.

https://doi.org/10.1007/s00281-015-0530-4

Chen Y, Wang ZL, Yeo M, Zhang QJ, López-Romero AE, Ding HP, et al. Epithelia-sensory neuron cross talk underlies cholestatic itch induced by lysophosphatidylcholine. Gastroenterology 2021; 161: 301-317.e16.

https://doi.org/10.1053/j.gastro.2021.03.049

Luo J, Feng J, Yu G, Yang P, Mack MR, Du J, et al. Transient receptor potential vanilloid 4-expressing macrophages and keratinocytes contribute differentially to allergic and nonallergic chronic itch. J Allergy Clin Immunol 2018; 141: 608-619.e7.

https://doi.org/10.1016/j.jaci.2017.05.051

Mascarenhas NL, Wang Z, Chang YL, Di Nardo A. TRPV4 mediates mast cell activation in cathelicidin-induced rosacea inflammation. J Invest Dermatol 2017; 137: 972-975.

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Akiyama T, Ivanov M, Nagamine M, Davoodi A, Carstens MI, Ikoma A, et al. Involvement of TRPV4 in serotonin-evoked scratching. J Invest Dermatol 2016; 136: 154-160.

https://doi.org/10.1038/JID.2015.388

Chen Y, Fang Q, Wang Z, Zhang JY, MacLeod AS, Hall RP, et al. Transient receptor potential vanilloid 4 ion channel functions as a pruriceptor in epidermal keratinocytes to evoke histaminergic itch. J Biol Chem 2016; 291: 10252-10262.

https://doi.org/10.1074/jbc.M116.716464

Kim S, Barry DM, Liu XY, Yin S, Munanairi A, Meng QT, et al. Facilitation of TRPV4 by TRPV1 is required for itch transmission in some sensory neuron populations. Sci Signal 2016; 9: ra71.

https://doi.org/10.1126/scisignal.aaf1047

Miyamoto T, Nojima H, Shinkado T, Nakahashi T, Kuraishi Y. Itch-associated response induced by experimental dry skin in mice. Jpn J Pharmacol 2002; 88: 285-292.

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Liu T, Han Q, Chen G, Huang Y, Zhao LX, Berta T, et al. Toll-like receptor 4 contributes to chronic itch, alloknesis, and spinal astrocyte activation in male mice. Pain 2016; 157: 806-817.

https://doi.org/10.1097/j.pain.0000000000000439

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Published

2022-02-22

How to Cite

Zhang, Q., Dias, F., Fang, Q., Henry, G., Wang, Z., Suttle, A., & Chen, Y. (2022). Involvement of Sensory Neurone-TRPV4 in Acute and Chronic Itch Behaviours. Acta Dermato-Venereologica, 102, adv00651. https://doi.org/10.2340/actadv.v102.1621

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