Immediate and delayed hypersensitivity reactions to birch pollen in patients with atopic dermatitis.
DOI:
https://doi.org/10.2340/0001555572193196Abstract
We investigated immediate and delayed hypersensitivity to birch pollen in 10 patients with atopic dermatitis (AD) who had experienced a worsening of their eczema during the birch pollen season. The patients were prick- and patch-tested and antigen-induced basophil histamine release and lymphocyte proliferation were measured. 9/10 birch pollen-allergic patients proved positive in the histamine release test and the results correlated with specific IgE levels measured by RAST. Birch pollen antigen induced lymphocyte proliferation in 6/10 patients, but a positive patch test result was obtained in only one case. Both peripheral blood monocytes and purified epidermal Langerhans' cells were able to present birch pollen antigen to T cells, although Langerhans' s cells seemed to function less efficiently in this respect.Downloads
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Published
1992-01-01
How to Cite
Räsänen, L., Reunala, T., Lehto, M., Virtanen, E., & Arvilommi, H. (1992). Immediate and delayed hypersensitivity reactions to birch pollen in patients with atopic dermatitis. Acta Dermato-Venereologica, 72(3), 193–196. https://doi.org/10.2340/0001555572193196
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