Topical salicylic acid interferes with UVB therapy for psoriasis.

Authors

  • B Kristensen
  • O Kristensen

DOI:

https://doi.org/10.2340/00015555713740

Abstract

Salicylic acid has been widely used in the topical treatment of psoriasis. Chemically it is closely related to paraaminobenzoic acid. Following in vitro studies indicating that salicylic acid might exhibit relevant UVB absorption, we found that salicylic acid had a clinically pronounced filter effect when applied prior to UVB exposure. The duration of photoprotection after application was more than 12 h, sometimes exceeding 24 h. In a prospective, randomized, double-blind, left-right comparison study in patients with psoriasis between emollients with and without salicylic acid, salicylic acid was shown to decrease the clearing rate significantly.

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Published

1991-01-01

How to Cite

Kristensen, B., & Kristensen, O. (1991). Topical salicylic acid interferes with UVB therapy for psoriasis. Acta Dermato-Venereologica, 71(1), 37–40. https://doi.org/10.2340/00015555713740

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Section

Articles