Effect of retinoic acid on the infiltration of murine melanoma cells into the type I collagen gel.
DOI:
https://doi.org/10.2340/00015555714144Abstract
Two lines of murine melanoma cells (B16 and Cloudman S91) were cultured on type I collagen gel and the effects of all-trans-retinoic acid on the growth and infiltration into the gel were assayed. In both lines, proliferation and the degree of infiltration were suppressed by the addition of all-trans-retinoic acid. The infiltration-inhibiting effect was expressed very rapidly and was dose-dependent at concentrations ranging from 10(-7) to 10(-5) M of all-trans-retinoic acid. These results suggest the anti-invasive effects of all-trans-retinoic acid on melanoma cells.Downloads
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Published
1991-01-01
How to Cite
Kono, T., Furukawa, M., Tanii, T., Taniguchi, S., Mizuno, N., Ishii, M., & Hamada, T. (1991). Effect of retinoic acid on the infiltration of murine melanoma cells into the type I collagen gel. Acta Dermato-Venereologica, 71(1), 41–44. https://doi.org/10.2340/00015555714144
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