Tetracycline does not affect the trauma- and leukotriene B4-induced intraepidermal accumulation of polymorphonuclear leukocytes.

Authors

  • A Chang
  • P Steegmans
  • P C van de Kerkhof

DOI:

https://doi.org/10.2340/00015555704648

Abstract

The transepidermal migration of polymorphonuclear leukocytes is a well established target for antipsoriatic therapies. Tetracycline, although inhibiting the movement of PMN, is not an effective treatment for psoriasis. In contrast to the inhibition of PMN chemotactic response to serum and bacterial products, the leukotriene B4-induced and trauma-induced intraepidermal accumulation of PMN was unaffected by tetracycline.

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Published

1990-01-01

How to Cite

Chang, A., Steegmans, P., & van de Kerkhof, P. C. (1990). Tetracycline does not affect the trauma- and leukotriene B4-induced intraepidermal accumulation of polymorphonuclear leukocytes. Acta Dermato-Venereologica, 70(1), 46–48. https://doi.org/10.2340/00015555704648

Issue

Section

Articles