Membrane-bound phospholipase C activity in normal and psoriatic epidermis.
DOI:
https://doi.org/10.2340/00015555705759Abstract
We report the quantification of a membrane-bound phospholipase C in human epidermis which is active against the physiologically relevant substrate, phosphatidylinositol 4,5-bisphosphate. The level of this enzyme is significantly increased in the psoriatic lesion, both on a weight and protein basis. Etiological implications of this observation are discussed.Downloads
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