Drug phototoxicity in mice

Authors

  • B Ljunggren
  • H Möller

DOI:

https://doi.org/10.2340/0001555558125130

Abstract

A series of agents with alleged photosensitizing properties has been studied in mice by a quantitative in vivo method for acute drug phototoxicity. The method, originally developed for phenothiazine studies, was found suitable for several drug groups with varying mechanism of action, such as tetracyclines, protoporphyrin and psoralens. In the sulfa group only sulfanilamide was active, although weakly. Phototoxicity in vivo, hitherto not demonstrated, was observed with griseofulvin, nalidixic acid, imperatorin, kynurenic acid and amiodarone.

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Published

1978-03-01

How to Cite

Ljunggren, B., & Möller, H. (1978). Drug phototoxicity in mice. Acta Dermato-Venereologica, 58(2), 125–130. https://doi.org/10.2340/0001555558125130

Issue

Section

Articles