Hidradenitis Suppurativa is Associated with Non-alcoholic Fatty Liver Disease: A Cross-sectional Study

Authors

  • Iris González-Villanueva
  • Cristina DeGracia
  • Mariana Planells
  • Inés Poveda
  • Pedro Álvarez
  • Luca Schneller-Pavalescu
  • Isabel Betlloch
  • Gregor B.E. Jemec
  • Jose M. Ramos
  • Jose C. Pascual

DOI:

https://doi.org/10.2340/00015555-3597

Keywords:

non-alcoholic fatty liver disease, hidradenitis suppurativa, acne inversa, liver steatosis, hepatic ultrasound

Abstract

Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of end-stage liver disease. The aim of this controlled cross-sectional study was to assess the association between NAFLD and hidradenitis suppurativa. NAFLD was assessed using hepatic ultrasound. A total of 125 patients with hidradenitis suppurativa and 120 patients without hidradenitis suppurativa were recruited, matched for age, sex and body mass index (<?25 or ??25 kg/m2), a risk factor related to NAFLD. Both groups presented similar proportions of overweight or obesity (89.6% vs 90%). Patients with hidradenitis suppurativa presented significantly higher prevalence of NAFLD compared with those with non- hidradenitis suppurativa (57.6% vs 31.7%, p?<?0.001). Multivariable analysis confirmed independent association between hidradenitis suppurativa and NAFLD (odds ratio 2.79, 95% confidence interval 1.48?5.25; p?=?0.001) besides age, body mass index, hypertension and hypertransaminasaemia. Hidradenitis suppurativa is significantly associated with the development of NALFD regardless of the presence of classic metabolic risk factors.

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Published

2020-08-18

How to Cite

González-Villanueva, I., DeGracia, C., Planells, M., Poveda, I., Álvarez, P., Schneller-Pavalescu, L., … C. Pascual, J. (2020). Hidradenitis Suppurativa is Associated with Non-alcoholic Fatty Liver Disease: A Cross-sectional Study. Acta Dermato-Venereologica, 100(15), 1–5. https://doi.org/10.2340/00015555-3597

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Articles