Toxic Epidermal Necrolysis Caused by Apalutamide: A Case Report of Treatment Using Etanercept with Conventional Steroid Therapy

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DOI:

https://doi.org/10.2340/actadv.v102.2243

Keywords:

toxic epidermal necrolysis, apalutamide, etanercept, steroid, tumour necrosis factor α

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References

Endo Y, Oka A, Uehara A, Toki S, Motegi SI, Ishikawa O, et al. Fatal case of toxic epidermal necrolysis due to apalutamide used as a novel prostate cancer drug. J Dermatol 2020; 47: e359-e360.

https://doi.org/10.1111/1346-8138.15510 DOI: https://doi.org/10.1111/1346-8138.15510

Sagawa N, Watanabe Y, Mizuno Y, Takahashi S, Watanabe T, Ikeda N, et al. A case of toxic epidermal necrolysis associated with apalutamide administration. J Cutan Immunol Allergy 2020; 3: 134-135.

https://doi.org/10.1002/cia2.12138 DOI: https://doi.org/10.1002/cia2.12138

Miyagawa A, Adachi T, Kobayashi Y, Takamiyagi S, Arakawa H, Futatsugi K, et al. Plasmapheresis as a promising treatment option in apalutamide-associated toxic epidermal necrolysis. J Dermatol 2022; 49: e102-e103

https://doi.org/10.1111/1346-8138.16248 DOI: https://doi.org/10.1111/1346-8138.16248

Umemura H, Koroki Y, Iwaki Y, Imanaka K, Kamabara T, Lopez-Gitlitz A, et al. Skin rash following administration of apalutamide in Japanese patients with advanced prostate cancer: an integrated analysis of the phase 3 SPARTAN and TITAN studies and a phase 1 open-label study. BMC Urology 2020; 20: 139.

https://doi.org/10.1186/s12894-020-00689-0 DOI: https://doi.org/10.1186/s12894-020-00689-0

Paradisi A, Abeni D, Bergamo F, Ricci F, Didona D, Didona B. Etanercept therapy for toxic epidermal necrolysis. J Am Acad Dermatol 2014; 71: 278-283.

https://doi.org/10.1016/j.jaad.2014.04.044 DOI: https://doi.org/10.1016/j.jaad.2014.04.044

Chang J, Girgis L. Clinical use of anti-TNF-α biological agents A: a guide for GPs. Aust Fam Physician 2007; 36: 1035-1038.

Published

2022-05-24

How to Cite

Osawa, K., Kiniwa, Y., Shimosato, Y., Midorikawa, H., Shirai, T., Sano, T., Nakamura, K., & Okuyama, R. (2022). Toxic Epidermal Necrolysis Caused by Apalutamide: A Case Report of Treatment Using Etanercept with Conventional Steroid Therapy. Acta Dermato-Venereologica, 102, adv00723. https://doi.org/10.2340/actadv.v102.2243

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