Comparison of Perceptions of Skin Condition, Product Use and Allergen Reactivity Between People with Psoriasis and Controls in the European Dermato-Epidemiology Network (EDEN) Fragrance Study

Authors

  • Fortunato Cassalia Centro Studi GISED, Bergamo, Italy; Dermatology Unit, Department of Medicine, University of Padova, Padua, Italy
  • Simone Cazzaniga Centro Studi GISED, Bergamo, Italy; Inselspital University Hospital of Bern, University of Bern, Bern, Switzerland.
  • Robert Ofenloch University Hospital Heidelberg, Section of Occupational Dermatology, Department of Dermatology, Germany.
  • Peter Elsner Dermatology, Allergology, Dermatopathology, SRH- Klinikum Gera, Germany.
  • Margarida Gonçalo University Hospital, Department of Dermatology; Faculty of Medicine, University of Coimbra, Dermatology, Portugal.
  • Marie-Louise Schuttelaar University Medical Center Groningen, Department of Dermatology, The Netherlands.
  • Åke Svensson University Hospital, Lund University, Department of Dermatology, Malmö, Sweden.
  • Elena Pezzolo 1. Centro Studi GISED, Bergamo, Italy; 2. Department of Dermatology, Ospedale San Bortolo, Vicenza;
  • Magnus Bruze Skåne University Hospital, Department of Occupational and Environmental Dermatology, Malmö, Sweden.
  • Luigi Naldi 1.Centro Studi GISED, Bergamo, Italy; 2. Department of Dermatology, Ospedale San Bortolo, Vicenza;

DOI:

https://doi.org/10.2340/actadv.v104.23513

Keywords:

psoriasis, skin dryness, skin sensitivity, allergen reactivity, patch test, neuro-immune inflammation

Abstract

Psoriasis, a chronic inflammatory skin disease, goes beyond visible symptoms and affects the general well-being of patients. The aim of this study is to understand how patients with psoriasis perceive their skin characteristics and reactivity to allergens. The study population includes 11,283 participants within the European Dermato-Epidemiology Network (EDEN) Fragrance study, covering several European regions. The study compared perceptions of skin dryness, sensitivity, product avoidance and reactivity to allergens between patients with psoriasis and controls, evaluating the potential influence of psoriasis severity. The results showed that subjects with psoriasis reported dry skin (71.1%) and sensitive skin (49.4%) more often than did controls (51.6% and 38.5%, respectively). Psoriasis patients were more likely to avoid specific products. Interestingly, there were no significant differences in patch-test results between the 2 groups and the severity of psoriasis did not have a consistent impact on these perceptions. In conclusion, people with psoriasis tend to perceive their skin as drier and more sensitive. Notably, the severity of psoriasis did not consistently influence these perceptions and objective reactivity to allergens did not align with subjective perception. Understanding these aspects is crucial for tailoring treatments to improve the well-being of patients with psoriasis, which warrants further research to explore subjective perceptions of skin well-being in patients with psoriasis.

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Published

2024-03-04

How to Cite

Cassalia, F., Cazzaniga, S., Ofenloch, R., Elsner, P., Gonçalo, M., Schuttelaar , M.-L., … Naldi, L. (2024). Comparison of Perceptions of Skin Condition, Product Use and Allergen Reactivity Between People with Psoriasis and Controls in the European Dermato-Epidemiology Network (EDEN) Fragrance Study. Acta Dermato-Venereologica, 104, adv23513. https://doi.org/10.2340/actadv.v104.23513

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