Cluster Infection Caused by a Terbinafine-resistant Dermatophyte at a Group Home: The First Case Series in Japan

Authors

  • Hiromitsu Noguchi Noguchi Dermatology Clinic, 1834-1 Namazu, Kashima-machi, Kamimashiki-gun, Kumamoto 861-3101, Japan
  • Tadahiko Matsumoto
  • Masataro Hiruma
  • Utako Kimura
  • Kayo Kashiwada-Nakamura
  • Masahide Kubo
  • Takashi Yaguchi
  • Satoshi Fukushima
  • Rui Kano

DOI:

https://doi.org/10.2340/00015555-3926

Keywords:

antifungal-resistance, efinaconazole, fosravuconazole, itraconazole, squalene epoxidase, terbinafine, Trichophyton rubrum

Abstract

Abstract is missing (Short communication)

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References

Yamada T, Maeda M, Alshahni MM, Tanaka R, Yaguchi T, Bontems O, et al. Terbinafine resistance of Trichophyton clinical isolates caused by specific point mutations in the squalene epoxidase gene. Antimicrob Agents Chemother 2017; 61: e00115–e00117.

Noguchi H, Matsumoto T, Hiruma M, Kimura U, Kano R, Yaguchi T, et al. Tinea unguium caused by terbinafine-resistant Trichophyton rubrum successfully treated with fosravuconazole. J Dermatol 2019; 46: e446–e447.

Hiruma J, Noguchi H, Hase M, Tokuhisa Y, Shimizu T, Ogawa T, et al. Epidemiological study of terbinafine-resistant dermatophytes isolated from Japanese patients. J Dermatol 2021; 48: 564–567.

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Digby SS, Hald M, Arendrup MC, Hjort SV, Kofoed K. Darier disease complicated by terbinafine-resistant Trichophyton rubrum: a case report. Acta Derm Venereol 2017; 97: 139–140.

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Yamada T, Yaguchi T, Tamura T, Pich C, Salamin K, Feuermann M, et al. Itraconazole resistance of Trichophyton rubrum mediated by the ABC transporter TruMDR2. Mycoses 2021; 64: 936–946.

Monod M, Feuermann M, Salamin K, Fratti M, Makino M, Alshahni MM, et al. Trichophyton rubrum azole resistance mediated by a new ABC transporter, TruMDR3. Antimicrob Agents Chemother 2019; 63: e00863–e00819.

Yamaguchi H. Potential of ravuconazole and its prodrugs as the new oral therapeutics for onychomycosis. Med Mycol J 2016; 57: E93–E110.

Watanabe S, Tsubouchi I, Okubo A. Efficacy and safety of fosravuconazole L-lysine ethanolate, a novel oral triazole antifungal agent, for the treatment of onychomycosis: a multicenter, double-blind, randomized phase III study. J Dermatol 2018; 45: 1151–1159.

Foley K, Gupta AK, Versteeg S, Mays R, Villanueva E, John D. Topical and device-based treatments for fungal infections of the toenails. Cochrane Database Syst Rev 2020; 1: CD012093.

Saunte DML, Pereiro-Ferreirós M, Rodríguez-Cerdeira C, Sergeev AY, Arabatzis M, Prohić A, et al. Emerging antifungal treatment failure of dermatophytosis in Europe: take care or it may become endemic. J Eur Acad Dermatol Venereol 2021; 35: 1582–1586.

Published

2021-09-28

How to Cite

Noguchi, H., Matsumoto, T., Hiruma, M., Kimura, U., Kashiwada-Nakamura, K., Kubo, M., Yaguchi, T., Fukushima, S., & Kano, R. (2021). Cluster Infection Caused by a Terbinafine-resistant Dermatophyte at a Group Home: The First Case Series in Japan. Acta Dermato-Venereologica, 101(9), adv00563. https://doi.org/10.2340/00015555-3926