Correlation Between Dermatology Life Quality Index and Psoriasis Area and Severity Index in Patients with Psoriasis Treated with Ustekinumab
DOI:
https://doi.org/10.2340/00015555-2833Keywords:
psoriasis, PASI, DLQI, correlation, ustekinumabAbstract
Monitoring of biological treatment efficacy for psoriasis is based on clinical evaluation and patient?s quality of life. However, long-term correlation between Psoriasis Area and Severity Index (PASI) and Dermatology Life Quality Index (DLQI) in real life has not been studied in patients treated with ustekinumab. All patients with psoriasis treated with ustekinumab at our department were included (n?=?120) in this study. Correlation analyses between the change in PASI and DLQI and the individual subquestions in DLQI were performed using Spearman?s rank correlation coefficient. A correlation value of 0.57 (p-value <?0.001) and 0.45 (p-value <?0.001) between PASI and DLQI were found in the period baseline ? 4 months and baseline ? 12 months, respectively. In DLQI subquestions, the greatest association was found for the questions on ?Symptoms and feelings?. Objective improvements in the severity of psoriasis were weakly to moderately associated with improvements in quality of life in patients with psoriasis treated with ustekinumab.Downloads
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2017 Jeanette Halskou Hesselvig, Alexander Egeberg, Nikolai Dyrberg Loft, Claus Zachariae, Kristian Kofoed, Lone Skov
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.
Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.
