The Role of Therapy in Impairing Quality of Life in Dermatological Patients: A Multinational Study

Authors

  • Flora N. Balieva
  • Andrew Y. Finlay
  • Jörg Kupfer
  • Lucía Tomas Aragones
  • Lars Lien
  • Uwe Gieler
  • Françoise Poot
  • Gregor B. E. Jemec
  • Laurent Misery
  • Lajos Kemeny
  • Francesca Sampogna
  • Henriët van Middendorp
  • Jon Anders Halvorsen
  • Thomas Ternowitz
  • Jacek C. Szepietowski
  • Nikolay Potekaev
  • Servando E. Marron
  • Ilknur K. Altunay
  • Sam S. Salek
  • Florence J. Dalgard

DOI:

https://doi.org/10.2340/00015555-2918

Keywords:

quality of life, HRQoL, DLQI, dermatological therapy, burden of skin disease, therapy burden

Abstract

Skin disease and its therapy affect health-related quality of life (HRQoL). The aim of this study was to measure the burden caused by dermatological therapy in 3,846 patients from 13 European countries. Adult outpatients completed questionnaires, including the Dermatology Life Quality Index (DLQI), which has a therapy impact question. Therapy issues were reported by a majority of patients with atopic dermatitis (63.4%), psoriasis (60.7%), prurigo (54.4%), hidradenitis suppurativa (54.3%) and blistering conditions (53%). The largest reduction in HRQoL attributable to therapy, as a percentage of total DLQI, adjusted for confounders, was seen in blistering conditions (10.7%), allergic/drug reactions (10.2%), psoriasis (9.9%), vasculitis/immunological ulcers (8.8%), atopic dermatitis (8.7%), and venous leg ulcers (8.5%). In skin cancer, although it had less impact on HRQoL, the reduction due to therapy was 6.8%. Treatment for skin disease contributes considerably to reducing HRQoL: the burden of dermatological treatment should be considered when planning therapy and designing new dermatological therapies.

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Published

2018-03-15

How to Cite

Balieva, F. N., Finlay, A. Y., Kupfer, J., Tomas Aragones, L., Lien, L., Gieler, U., Poot, F., Jemec, G. B. E., Misery, L., Kemeny, L., Sampogna, F., van Middendorp, H., Halvorsen, J. A., Ternowitz, T., Szepietowski, J. C., Potekaev, N., Marron, S. E., Altunay, I. K., S. Salek, S., & J. Dalgard, F. (2018). The Role of Therapy in Impairing Quality of Life in Dermatological Patients: A Multinational Study. Acta Dermato-Venereologica, 98(6), 563–569. https://doi.org/10.2340/00015555-2918

Issue

Vol. 98 No. 6 (2018): June

Section

Articles

License

Copyright (c) 2018 Flora N. Balieva, Andrew Y. Finlay, Jörg Kupfer, Lucía Tomas Aragones, Lars Lien, Uwe Gieler, Françoise Poot, Gregor B. E. Jemec, Laurent Misery, Lajos Kemeny, Francesca Sampogna, Henriët van Middendorp, Jon Anders Halvorsen, Thomas Ternowitz, Jacek C. Szepietowski, Nikolay Potekaev, Servando E. Marron, Ilknur K. Altunay, Sam S. Salek, Florence J. Dalgard

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.

Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.

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